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5825 ABCD3

5825

ABCD3

ATP binding cassette subfamily D member 3

protein-coding

Homo sapiens

基因描述

Type Description
Definition ATP binding cassette subfamily D member 3

研究结论

Date Results Publications
2020-05-16 10:11:00 In HEK293 cells, the D-bifunctional protein (HSD17B4) and the peroxisomal ABC transporter ABCD3 are essential in peroxisomal oxidation of lauric and palmitic acid. 30540494
2017-02-18 10:57:00 ABCD1 and ABCD2 are involved in the transport of long and very long chain fatty acids (VLCFA) or their CoA-derivatives into peroxisomes with different substrate specificities, while ABCD3 is involved in the transport of branched chain acyl-CoA into peroxisomes.ABCD4 is deduced to take part in the transport of vitamin B12 from lysosomes into the cytosol. 27766264
2017-02-04 12:39:00 Data show that ACBD3 can recruit PI4KB to model membranes as well as redirect PI4KB to cellular membranes where it is not naturally found. Also, results show that ACBD3 regulates the enzymatic activity of PI4KB kinase through membrane recruitment rather than allostery. 27009356
2017-02-04 12:37:00 The N-terminal motif of PMP70 suppresses cotranslational targeting to the endoplasmic reticulum. 26711236
2016-01-16 10:55:00 Increased ABCD3 expression correlates with Gleason 25802834

名称对应

Type IDs
Synonymous ABC43, CBAS5, PMP70, PXMP1, ZWS2
Gene
UniProtKB-ID: ABCD3_HUMAN
UniprotKB: P28288
UniParc: UPI000006D8FD, UPI0000352C1B, UPI000004C4C7
EMBL: X83475, AC118469, AL138758, BC009712, X83486, X83470, X83484, X83477, BC068509, X83479, X83468, BT006644, X83483, AC093117, X83482, X83488, X83474, X83478, X83476, X58528, X83471, X83485, X83467, X83481, X83469, X83487, X83472, X83473, M81182, X83489, X83480, CH471097
Ensembl: ENSG00000117528
KO: hsa:5825
Nucleutide sequences
EMBL-CDS: AAH09712.1, EAW73049.1, AAP35290.1, AAH68509.1, CAA58470.1, AAA60128.1, EAW73048.1, EAW73050.1, EAW73047.1, CAA41416.1
Ensembl_TRS: ENST00000315713, ENST00000370214
Protein sequencees
Ensembl_PRO: ENSP00000359233, ENSP00000326880
RefSeq: XP_006710865.2, NP_002849.1, NP_001116146.1, XP_011540179.1
Others
UniRef100: UniRef100_P28288
UniRef90: UniRef90_P28288
UniRef50: UniRef50_P28288
UniGene: Hs.700576
CCDS: CCDS44175.1, CCDS749.1

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