| Type | Description |
|---|---|
| Definition | matrix metallopeptidase 19 |
| Date | Results | Publications |
|---|---|---|
| 2017-11-04 11:56:00 | this study shows that MMP-19 deficiency causes aggravation of colitis due to defects in innate immune cell function | 26555704 |
| 2016-12-17 11:55:00 | Estrogen receptor beta target gene, where ERbeta requires a specific Sp1 site on the MMP-19 promoter to mediate ligand dependent transcription | 26700939 |
| 2015-05-16 10:40:00 | These findings suggest that, in lung fibroblasts, MMP-19 has strong regulatory effects on the synthesis of key ECM components, on fibroblast to myofibroblast differentiation, and in migration and proliferation. | 25575513 |
| 2013-06-15 11:35:00 | MMP-19-deficiency improves the development of hepatic fibrosis through the diminished replacement of physiological extracellular matrix with fibrotic deposits in the beginning of the injury | 23056273 |
| 2012-12-29 10:02:00 | In WT mice, PTGS2 was significantly increased in bronchoalveolar lavage and lung tissues after bleomycin-induced fibrosis, but not in Mmp19-/- mice. Inhibition of Mmp-19 by siRNA resulted in inhibition of Ptgs2 at mRNA and protein levels. | 22859522 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
MMP19_MOUSE,
Q2KHP2_MOUSE,
Q3UW97_MOUSE
UniprotKB:
Q9JHI0,
Q2KHP2,
Q3UW97
UniParc:
UPI00005ABCBF,
UPI00000225DC
EMBL:
AC131081,
AF153199,
BC112966,
AK086808,
AF162446,
AK136517,
AF155221
Ensembl:
ENSMUSG00000025355
KO:
mmu:58223
|
| Nucleutide sequences |
EMBL-CDS:
AAG29880.1,
BAC39747.1,
AAF73292.1,
AAF80464.1,
AAI12967.1,
BAE23019.1
Ensembl_TRS:
ENSMUST00000026411,
ENSMUST00000219404
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000026411,
ENSMUSP00000151437
RefSeq:
NP_001157669.1,
NP_067387.1
|
| Others |
UniRef100:
UniRef100_Q9JHI0
UniRef90:
UniRef90_Q9JHI0
UniRef50:
UniRef50_Q99542
UniGene:
Mm.131266
CCDS:
CCDS24292.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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