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58208 Bcl11b

58208

Bcl11b

B cell leukemia/lymphoma 11B

protein-coding

Mus musculus

基因描述

Type Description
Definition B cell leukemia/lymphoma 11B

研究结论

Date Results Publications
2021-04-17 13:13:00 Gut commensals suppress interleukin-2 production through microRNA-200/BCL11B and microRNA-200/ETS-1 axes in lamina propria leukocytes of murine large intestine. 33162030
2020-07-18 11:10:00 Bcl11b works substantially differently in these two cell types. 31653691
2020-06-27 11:28:00 BCL11B suppression is induced by chimeric antigen receptor and propagates NK-like cell development 31479431
2020-05-09 10:46:00 Bcl11b, in association with Foxp3, is primarily responsible in establishing a Treg-specific gene activation program. Bcl11b restricts misdirected recruitment of Foxp3 to sites, which would otherwise result in an altered Treg transcriptome profile. 31457081
2020-05-09 10:46:00 Bcl11b controlled expression of essential Treg program genes at steady state and in inflammation. Bcl11b bound to genomic regulatory regions of Treg program genes in both human and mouse Treg cells, overlapping with Foxp3 binding; these genes showed altered chromatin accessibility in the absence of Bcl11b. 31457080

名称对应

Type IDs
Synonymous 9130430L19Rik, AI604821, B630002E05Rik, BCL-11B, Ctip2, Rit1
Gene
UniProtKB-ID: BC11B_MOUSE, A0A0R4J1E1_MOUSE
UniprotKB: Q99PV8, A0A0R4J1E1
UniParc: UPI00000E6F29, UPI00000287AF, UPI00000E71C7, UPI000023FEFB
EMBL: AB043553, AF186019, AC119219, AC119921, AB043551, BC019503, AK088588, AB043583
Ensembl: ENSMUSG00000048251
KO: mmu:58208
Nucleutide sequences
EMBL-CDS: AAF63683.1, BAC40438.1, BAB32730.1, AAH19503.1, BAB32728.1, BAB32729.1
Ensembl_TRS: ENSMUST00000109891, ENSMUST00000066060, ENSMUST00000109887
Protein sequencees
Ensembl_PRO: ENSMUSP00000068258, ENSMUSP00000105517, ENSMUSP00000105513
RefSeq: XP_006516179.1, NP_001273272.1, XP_036013441.1, XP_011242454.1, XP_006516173.1, XP_006516174.1, XP_017170634.1, XP_036013440.1, XP_011242455.1, XP_036013442.1, XP_006516177.1, XP_006516176.1, NP_001073352.1, XP_017170632.1, XP_006516178.1, XP_036013439.1, NP_067374.2, XP_017170633.1
Others
UniRef100: UniRef100_Q99PV8, UniRef100_A0A0R4J1E1
UniRef90: UniRef90_A0A0R4J1E1, UniRef90_Q99PV8
UniRef50: UniRef50_Q99PV8, UniRef50_F7A9E4
UniGene: Mm.392694
CCDS: CCDS70419.1, CCDS36553.1, CCDS36552.1

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