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58193 Extl2

58193

Extl2

exostoses (multiple)-like 2

protein-coding

Mus musculus

基因描述

Type Description
Definition exostoses (multiple)-like 2

研究结论

Date Results Publications
2021-01-16 15:53:00 Aberrant glycosaminoglycan biosynthesis by tumor suppressor EXTL2 deficiency promotes liver inflammation and tumorigenesis through Toll-like 4 receptor signaling. 32347583
2018-04-28 10:24:00 Data show that exostosin-like 2 (EXTL2) controls fibroblast growth factor 2 (FGF2) signaling through regulation of heparan sulfate biosynthesis. 29305908
2015-01-17 12:25:00 EXTL2 controls liver regeneration and aortic calcification through xylose kinase-dependent regulation of glycosaminoglycan biosynthesis.[review] 24176719
2013-10-19 11:21:00 EXTL2-mediated regulation of glycosaminoglycans synthesis is important for tissue regeneration processes following liver injury. 23734945
2013-06-01 11:48:00 EXTL2 functions to suppress GAG biosynthesis that is enhanced by a xylose kinase and the EXTL2-dependent mechanism that regulates GAG biosynthesis might be a "quality control system" for proteoglycans 23395820

名称对应

Type IDs
Synonymous 3000001D04Rik, AW146439
Gene
UniProtKB-ID: EXTL2_MOUSE, Q3TSR0_MOUSE, Q8C089_MOUSE
UniprotKB: Q9ES89, Q3TSR0, Q8C089
UniParc: UPI00000EA325, UPI00001EFDBA, UPI0000001A88
EMBL: AK019370, BC094444, AF200973, AK161866, AC108909, AK032016, BC031438
Ensembl: ENSMUSG00000027963
KO: mmu:58193
Nucleutide sequences
EMBL-CDS: AAG17542.1, BAB31683.2, AAH31438.1, AAH94444.1, BAE36615.1, BAC27649.1
Ensembl_TRS: ENSMUST00000106502, ENSMUST00000029575, ENSMUST00000106501
Protein sequencees
Ensembl_PRO: ENSMUSP00000029575, ENSMUSP00000102111, ENSMUSP00000102110
RefSeq: XP_036019091.1, NP_001156986.1, XP_011238479.1, NP_001156987.1, NP_067363.3, XP_030108599.1, XP_017175163.1
Others
UniRef100: UniRef100_Q9ES89, UniRef100_Q8C089
UniRef90: UniRef90_Q9ES89
UniRef50: UniRef50_Q9UBQ6
UniGene: Mm.41739
CCDS: CCDS17784.1

全选

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