| Type | Description |
|---|---|
| Definition | nectin cell adhesion molecule 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-05-30 10:57:00 | ubiquitination of Nectin2 promotes its degradation and is responsible for protein intracellular retention and inhibition of the ubiquitin pathway results in increased Nectin2 surface expression and enhances tumor cell susceptibility to NK cell cytotoxicity | 30888046 |
| 2020-04-11 10:13:00 | we demonstrate that PVRIG and PVRL2 are expressed in human cancers and the PVRIG-PVRL2 and TIGIT-PVR pathways are nonredundant inhibitory signaling pathways. | 30659054 |
| 2019-08-31 13:37:00 | Structural analysis of currently available homodimeric structures of both nectin-2 and N-cadherin followed by molecular docking as well as complementary mutagenesis studies revealed the binding interface of this novel interaction. | 30183103 |
| 2019-06-29 12:14:00 | Nectin cell adhesion molecule 2 (Nectin-2) expression in ovarian cancer may support tumor cell adhesion, leading to growth and lymph node metastasis. | 30843637 |
| 2018-06-09 10:42:00 | Nectin-2 mutation in men with severe teratospermia | 28689229 |
| Type | IDs |
|---|---|
| Synonymous | CD112, HVEB, PRR2, PVRL2, PVRR2 |
| Gene |
UniProtKB-ID:
NECT2_HUMAN
UniprotKB:
Q92692
UniParc:
UPI000002B1F5,
UPI000004A2BF
EMBL:
AF044966,
AF044962,
X80038,
BC003091,
AF044964,
AF050154,
CH471126,
AF044963,
CR456818,
AF058448,
AF044967,
AK291330,
AF044968
Ensembl:
ENSG00000130202
KO:
hsa:5819
|
| Nucleutide sequences |
EMBL-CDS:
AAC82348.1,
EAW57298.1,
AAH03091.1,
AAD02503.1,
CAA56342.1,
BAF84019.1,
CAG33099.1,
AAC23797.1
Ensembl_TRS:
ENST00000252483,
ENST00000252485
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000252483,
ENSP00000252485
RefSeq:
NP_001036189.1,
NP_002847.1
|
| Others |
UniRef100:
UniRef100_Q92692
UniRef90:
UniRef90_Q92692
UniRef50:
UniRef50_Q92692
UniGene:
Hs.655455
CCDS:
CCDS42576.1,
CCDS12645.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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