| Type | Description |
|---|---|
| Definition | prokineticin receptor 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-07-06 10:51:00 | Upon high fat diet exposure, PKR1 (tcf-/-) mice displayed excessive fat deposition in the atrioventricular groove, perivascular area, and pericardium, which was accompanied by an impaired vascular network and cardiac dysfunction. | 29038558 |
| 2018-11-17 10:56:00 | The study shows that PK2beta ligand, a splice variant of prokineticin 2, is able to modulate and drive signaling through prokineticin receptor 1. | 30253862 |
| 2018-02-10 10:39:00 | The authors discovered that PKR1 regulates epicardial-mesenchymal transition (EMT) for epicardial-derived progenitor cell (EPDC), formation. This event affects at least three consequential steps during heart development: (i) EPDC and cardiomyocyte proliferation involved in thickening of an outer compact ventricular chamber wall, (ii) rhythmicity, (iii) formation of coronary circulation. | 27150455 |
| 2017-08-26 10:53:00 | These results establish PKR1 via NFATc3 as a crucial modifier of mesenchymal-epithelial transition processing to the development of nephron. | 27084889 |
| 2016-12-17 10:49:00 | show that MRAP2 significantly and specifically inhibits PKR1 signaling. | 26829592 |
| Type | IDs |
|---|---|
| Synonymous | EG-VEGFR1, Gpr73, Pk-r1, Pkr1 |
| Gene |
UniProtKB-ID:
PKR1_MOUSE
UniprotKB:
Q9JKL1
UniParc:
UPI0000023395
EMBL:
BC059003,
CH466523,
AK134279,
AF487278,
AF236082,
AK156734
Ensembl:
ENSMUSG00000049409
KO:
mmu:58182
|
| Nucleutide sequences |
EMBL-CDS:
AAM49570.1,
EDK99210.1,
BAE33828.1,
BAE22080.1,
AAH59003.1,
AAF43706.1
Ensembl_TRS:
ENSMUST00000204682,
ENSMUST00000050887
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000059034,
ENSMUSP00000144999
RefSeq:
XP_006506496.1,
XP_006506495.1,
NP_067356.2,
NP_001342584.1
|
| Others |
UniRef100:
UniRef100_Q9JKL1
UniRef90:
UniRef90_Q9JKL1
UniRef50:
UniRef50_Q8TCW9
UniGene:
Mm.333226
CCDS:
CCDS20323.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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