| Type | Description |
|---|---|
| Definition | nectin cell adhesion molecule 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:30:00 | Hepatocellular Carcinoma Cells Up-regulate PVRL1, Stabilizing PVR and Inhibiting the Cytotoxic T-Cell Response via TIGIT to Mediate Tumor Resistance to PD1 Inhibitors in Mice. | 32275969 |
| 2021-03-20 13:33:00 | Generation of an Oncolytic Herpes Simplex Viral Vector Completely Retargeted to the GDNF Receptor GFRalpha1 for Specific Infection of Breast | 33233403 |
| 2020-07-11 10:12:00 | Nectin-1-expressing cells acquire dye-labeled cytoplasmic proteins synchronously with nectin-4, a process most active during cell adhesion. | 31331966 |
| 2019-12-07 11:06:00 | Nectin-1 directly interacts with CD96 in vitro. The binding site for CD96 is located on the nectin-1 V-domain, which comprises a canonical interface that is shared by nectins to promote cell adhesion. The affinity of nectin-1 for CD96 is lower than for other nectins such as nectin-3 and nectin-1 itself. | 30759143 |
| 2019-11-02 10:42:00 | Brain tumor expression of nectin-1 may be a useful biomarker to predict patient response to oHSV. | 30224769 |
| Type | IDs |
|---|---|
| Synonymous | CD111, CLPED1, ED4, HIgR, HV1S, HVEC, OFC7, PRR, PRR1, PVRL1, PVRR, PVRR1, SK-12, nectin-1 |
| Gene |
UniProtKB-ID:
NECT1_HUMAN
UniprotKB:
Q15223
UniParc:
UPI000004A2BE,
UPI000002B1F3,
UPI000002B1F4
EMBL:
AF252867,
AF196769,
AF196770,
AF196774,
AF196768,
BC104948,
AF196773,
AY029539,
AF196771,
AF196772,
BC113471,
X76400,
AF060231
Ensembl:
ENSG00000110400
KO:
hsa:5818
|
| Nucleutide sequences |
EMBL-CDS:
AAI04949.1,
AAI13472.1,
AAG16649.1,
AAK33124.1,
AAG16648.1,
AAC23798.1,
CAA53980.2
Ensembl_TRS:
ENST00000264025,
ENST00000341398,
ENST00000340882
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000344974,
ENSP00000345289,
ENSP00000264025
RefSeq:
NP_976030.1,
NP_976031.1,
NP_002846.3
|
| Others |
UniRef100:
UniRef100_Q15223
UniRef90:
UniRef90_Q15223
UniRef50:
UniRef50_Q15223
UniGene:
Hs.334846
CCDS:
CCDS8427.1,
CCDS8425.1,
CCDS8426.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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