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58178 Sorcs1

58178

Sorcs1

sortilin-related VPS10 domain containing receptor 1

protein-coding

Mus musculus

基因描述

Type Description
Definition sortilin-related VPS10 domain containing receptor 1

研究结论

Date Results Publications
2020-02-29 11:06:00 SorCS1-mediated sorting in dendritic endosomes controls Nrxn axonal surface polarization required for proper synapse development and function. 31658245
2020-02-22 13:04:00 SorCS1 and SorLA expression were markedly reduced in the frontal cerebral cortex and to a minor extent in the hippocampus, whereas SorCS3 expression was solely reduced in the frontal cerebral cortex 31095505
2019-02-16 11:32:00 our findings identified a novel role for VPS10P domain receptors SORCS1 and SORCS3 in hypothalamic control of metabolism through regulation of orexigenic peptide production. 29440124
2016-10-22 12:10:00 Male mice with either the APP/PSEN1 or Sorcs1 -/- genotype displayed earlier onset and persistent impairment in both glucose homeostasis and in learning behavior. 26916443
2016-01-16 12:23:00 SorCS1 and APP share trafficking pathways and that SorCS1c can retain APP from insertion into anterograde transport vesicles 26119586

名称对应

Type IDs
Synonymous Sorcs, mSorCS
Gene
UniProtKB-ID: Q8BSV0_MOUSE, A0A1B0GRC4_MOUSE, A0A1B0GRN1_MOUSE, A0A1B0GT94_MOUSE
UniprotKB: Q8BSV0, A0A1B0GRC4, A0A1B0GRN1, A0A1B0GT94
UniParc: UPI00042CE067, UPI0000565D66, UPI0000D62E77, UPI00000EAC4F
EMBL: AK030440, AC158463, AC100726, AC101745, AC101735, AC122294, AC131103
Ensembl: ENSMUSG00000043531
KO: mmu:58178
Nucleutide sequences
EMBL-CDS: BAC26965.1
Ensembl_TRS: ENSMUST00000209413, ENSMUST00000211687, ENSMUST00000209783
Protein sequencees
Ensembl_PRO: ENSMUSP00000147463, ENSMUSP00000147591, ENSMUSP00000148254
RefSeq: XP_006527307.1, XP_017173754.1, XP_006527306.1, NP_001277285.1, NP_001347386.1, NP_067352.2, NP_001239430.1, XP_030106868.1, XP_030106869.1
Others
UniRef100: UniRef100_A0A1B0GRN1, UniRef100_Q8BSV0, UniRef100_A0A1B0GRC4, UniRef100_A0A1B0GT94
UniRef90: UniRef90_F1LUZ4, UniRef90_Q9JLC4
UniRef50: UniRef50_Q8WY21, UniRef50_Q8WY21-4
UniGene: Mm.313672

全选

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