| Type | Description |
|---|---|
| Definition | Rhesus blood group-associated B glycoprotein |
| Date | Results | Publications |
|---|---|---|
| 2017-03-22 09:09:00 | Utilizing a structural homology analysis to AmtB, we have identified residues in Rhbg that are implicated in ion transport function. We introduced mutations into these residues and evaluated their function using measurements of intracellular pH (pHi), surface pH (pHs), and whole cell currents (I) that can distinguish between NH3 and NH4+ signals. Our results identified critical amino acids that affect transport. | 27681563 |
| 2015-12-10 17:56:00 | We characterized ammonia and ammonium (NH3/NH4 (+)) transport by the rhesus-associated (Rh) glycoproteins RhAG, Rhbg, and Rhcg expressed in Xenopus oocytes. We used ion-selective microelectrodes and two-electrode voltage clamp to measure changes in intracellular pH, surface pH, and whole cell currents induced by NH3/NH4 (+) and methyl amine/ammonium (MA/MA(+)). | 26354748 |
| 2014-07-19 11:43:00 | Rh B Glycoprotein (Rhbg) and Rh C Glycoprotein (Rhcg) are identified as ammonia transporters. They are expressed in specific cell populations and membrane domains in distal renal epithelial cells, where they facilitate ammonia secretion. | 24647713 |
| 2014-05-03 11:27:00 | Rhbg is critically important in the renal response to metabolic acidosis. in mice with intact Rhbg expression, metabolic acidosis does not induce maximal changes in PEPCK, NHE-3, and GS expression despite the presence of persistent metabolic acidosis. | 24338819 |
| 2014-03-22 11:21:00 | highly expressed in specific cells in the male reproductive tract | 23904565 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
RHBG_MOUSE
UniprotKB:
Q8BUX5
UniParc:
UPI0000020B6E
EMBL:
AK081882,
AY254685,
AF193808,
BC029236
Ensembl:
ENSMUSG00000104445
KO:
mmu:58176
|
| Nucleutide sequences |
EMBL-CDS:
BAC38359.1,
AAP81167.1,
AAF19371.1,
AAH29236.1
Ensembl_TRS:
ENSMUST00000171887
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000130767
RefSeq:
XP_006501889.1,
NP_067350.2
|
| Others |
UniRef100:
UniRef100_Q8BUX5
UniRef90:
UniRef90_Q8BUX5
UniRef50:
UniRef50_Q9H310-2
UniGene:
Mm.103777
CCDS:
CCDS17466.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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