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58152 scn8aa

58152

scn8aa

sodium channel, voltage gated, type VIII, alpha subunit a

protein-coding

Danio rerio

基因描述

Type Description
Definition sodium channel, voltage gated, type VIII, alpha subunit a

研究结论

Date Results Publications
2010-12-11 10:39:00 Genetic mapping identifies the gene encoding NaV1.6a (scn8aa) as a potential candidate for nav. NaV1.6a is required for touch-induced activation of the swim locomotor network. 20225246
2010-09-27 11:29:00 transdifferentiating neurons are increased in number in larvae that have a mutant voltage-gated sodium channel gene, scn8aa. 20685733
2010-01-21 00:00:00 The correctly spliced Na(v)1.6 mRNA of MO3 morphants is 6% relative to that of the wild-type embryos. Na(v)1.6-targeted MO attenuate the spontaneous contraction, tactile sensitivity, and swimming in comparison with a scrambled or mutated morpholino. 17687633
2010-01-21 00:00:00 Results demonstrate that these four regulatory elements function cooperatively to enhance scn8aa expression in the zebrafish nervous system 18729213
2010-01-21 00:00:00 Nav1.6a knockdown altered axonal morphologies of some but not all motoneurons. 16943272

名称对应

Type IDs
Synonymous Nav1.6, scn8a
Gene
UniProtKB-ID: Q9DF53_DANRE
UniprotKB: Q9DF53
UniParc: UPI00000FBBD5
EMBL: AF297658, CR376824
Ensembl: ENSDARG00000005775
KO: dre:58152
Nucleutide sequences
EMBL-CDS: AAG18440.1
Ensembl_TRS: ENSDART00000022042
Protein sequencees
Ensembl_PRO: ENSDARP00000024690
RefSeq: NP_571703.1, XP_009295146.1, XP_021325517.1, XP_021325516.1, XP_021325518.1, XP_009295149.1, XP_005162325.1
Others
UniRef100: UniRef100_Q9DF53
UniRef90: UniRef90_Q9DF53
UniRef50: UniRef50_P35498-2
UniGene: Dr.82518

全选

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研究热度

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