| Type | Description |
|---|---|
| Definition | purine rich element binding protein A |
| Date | Results | Publications |
|---|---|---|
| 2019-07-06 12:04:00 | Silencing of miR-144 significantly decreased the migration, invasion and colony formation potential of esophageal carcinoma cell line KYSE-410 | 29940778 |
| 2017-12-16 11:02:00 | Three genes in our epilepsy cohort (COQ4, DNM1, and PURA), accounting for 14% (3/21) of all novel genetic etiologies identified in patients with epilepsy, were subsequently confirmed in independent publications. | 26795593 |
| 2017-06-03 10:28:00 | PURA may be a potential target of miR-144 and observed downregulation of PURA may be caused by increased expression of miR-144. The other predicted target of miR-144 SPRED1, was found to be downregulated in 69 per cent EC tissues as compared to matched distant non-malignant tissues. | 27748283 |
| 2016-12-17 12:06:00 | The results of this study emphasizes the importance of stress granules in ALS pathogenesis and identifies Pur-alpha as a novel regulator of cytoplasmic stress granules dynamics. | 26728149 |
| 2015-07-25 11:13:00 | These findings provide definitive evidence for the role of PURA in causing a variable syndrome of neurodevelopmental delay, learning disability, neonatal hypotonia, feeding difficulties, abnormal movements and epilepsy in humans | 25342064 |
| Type | IDs |
|---|---|
| Synonymous | MRD31, PUR-ALPHA, PUR1, PURALPHA |
| Gene |
UniProtKB-ID:
PURA_HUMAN
UniprotKB:
Q00577
UniParc:
UPI0000132B76
EMBL:
U02098,
M96684
Ensembl:
ENSG00000185129
KO:
hsa:5813
|
| Nucleutide sequences |
EMBL-CDS:
AAA60229.1
Ensembl_TRS:
ENST00000331327,
ENST00000651386
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000499133,
ENSP00000332706
RefSeq:
NP_005850.1
|
| Others |
UniRef100:
UniRef100_Q00577
UniRef90:
UniRef90_Q00577
UniRef50:
UniRef50_Q00577
UniGene:
Hs.443121,
Hs.733524
CCDS:
CCDS4220.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员