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5810 RAD1

5810

RAD1

RAD1 checkpoint DNA exonuclease

protein-coding

Homo sapiens

基因描述

Type Description
Definition RAD1 checkpoint DNA exonuclease

研究结论

Date Results Publications
2017-04-08 10:45:00 Dominant alleles of RAD51, TP53 and XRCC1 combined genotypes indicated a strong protective role against hereditary breast cancer. 26954070
2015-11-07 10:27:00 Intramolecular binding of the rad9 C-terminus in the checkpoint clamp Rad9-Hus1-Rad1 is closely linked with its DNA binding. 26088138
2012-08-25 10:45:00 Data show models for the ternary PCNA/FEN1/DNA and Rad9-Rad1-Hus1 (9-1-1 complex)/FEN1/DNA assemblies. 22586102
2012-04-07 10:27:00 The RAD1 is loaded to damaged sites where it serves as a platform for the selective recruitment of checkpoint and repair proteins. 21978893
2010-11-27 10:09:00 CK2 plays a crucial role in the ATR-dependent checkpoint pathway through its ability to phosphorylate Ser-341 and Ser-387 of the Rad9 subunit of the Rad9-Hus1-Rad1 complex 20545769

名称对应

Type IDs
Synonymous HRAD1, REC1
Gene
UniProtKB-ID: RAD1_HUMAN, A0A024R045_HUMAN
UniprotKB: O60671, A0A024R045
UniParc: UPI0001C2FAD9, UPI000003159B, UPI00000723BC
EMBL: AB183821, AF084513, CH471119, AJ004975, BT006908, BC006837, AK002112, AF076841, BC037857, AF058392, AF084512, AF011905, BC009804, AF090170, AF030933, DQ451401, AB183822, AF073524, AJ004974, AF074717
Ensembl: ENSG00000113456
KO: hsa:5810
Nucleutide sequences
EMBL-CDS: AAH37857.1, AAP35554.1, BAG51017.1, AAH06837.1, CAA06249.1, ABD96829.1, AAC95523.1, AAC95603.1, BAD86790.1, AAC35549.1, BAD86789.1, CAA06248.1, AAC95427.1, AAC14138.1, AAC35550.1, AAH09804.1, AAC27243.1, AAC95466.1, AAC98093.1, EAW55904.1, EAW55906.1, EAW55907.1, EAW55908.1
Gene_ORFName: hCG_37731
Ensembl_TRS: ENST00000382038, ENST00000325577, ENST00000341754
Protein sequencees
Ensembl_PRO: ENSP00000340879, ENSP00000313467, ENSP00000371469
RefSeq: NP_002844.1
Others
UniRef100: UniRef100_O60671
UniRef90: UniRef90_O60671
UniRef50: UniRef50_O60671
UniGene: Hs.38114
CCDS: CCDS3905.1

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