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5799 PTPRN2

5799

PTPRN2

protein tyrosine phosphatase receptor type N2

protein-coding

Homo sapiens

基因描述

Type Description
Definition protein tyrosine phosphatase receptor type N2

研究结论

Date Results Publications
2020-10-03 12:54:00 The association of genetically controlled CpG methylation (cg158269415) of protein tyrosine phosphatase, receptor type N2 (PTPRN2) with childhood obesity. 30890718
2017-08-26 11:26:00 Copy-number variations are enriched for PTPRN2 and other neurodevelopmental genes in children with developmental coordination disorder. 27489308
2017-05-20 10:50:00 Haplotype-dependent allele-specific methylation of PTPRN2 gene is associated with neurological disorders. 27153397
2016-05-07 10:23:00 Reduction in plasma membrane PI(4,5)P2 abundance by PTPRN2 and PLCbeta1 releases the PI(4,5)P2-binding protein cofilin from its inactive membrane-associated state into the cytoplasm where it mediates actin turnover dynamics. 26620550
2015-12-05 11:52:00 Data indicate the X-ray structure of the mature ectodomain of mature ectodomain of phogrin/IA-2beta (PTPRN2) (ME phogrin) at pH 7.4 and 4.6. 25421040

名称对应

Type IDs
Synonymous IA-2beta, IAR, ICAAR, PTPRP, R-PTP-N2
Gene
UniProtKB-ID: PTPR2_HUMAN, E7EM83_HUMAN, I6L9F8_HUMAN
UniprotKB: Q92932, E7EM83, I6L9F8
UniParc: UPI000002E7C7, UPI00001AFFA3, UPI00001AF931, UPI00003782EB, UPI00018814AD, UPI00017BE7A9
EMBL: AC011899, KF458646, AB002385, AC005481, AC093662, AF007555, U66702, KF510999, BC034040, AC093856, AC006003, U81561, AC078942, AC019043, Y08569, AC125243, AC006372, KF510998, BC071570
Ensembl: ENSG00000155093
KO: hsa:5799
Nucleutide sequences
EMBL-CDS: AAH34040.1, AAB68603.1, CAA69880.1, AAB63600.1, AAC50742.1, BAA20841.2, AAH71570.1
Ensembl_TRS: ENST00000389418, ENST00000389416, ENST00000389413, ENST00000409483
Protein sequencees
Ensembl_PRO: ENSP00000374067, ENSP00000374064, ENSP00000374069, ENSP00000387114
RefSeq: NP_570858.2, NP_570857.2, XP_011514750.1, XP_011514748.1, NP_002838.2, XP_016867965.1, XP_011514751.1, XP_016867964.1, NP_001295197.1, XP_011514749.1, NP_001295196.1
Others
UniRef100: UniRef100_I6L9F8, UniRef100_E7EM83, UniRef100_Q92932
UniRef90: UniRef90_I6L9F8, UniRef90_Q92932, UniRef90_Q92932-2
UniRef50: UniRef50_I6L9F8, UniRef50_Q92932
UniGene: Hs.490789
CCDS: CCDS5947.1, CCDS5948.1, CCDS5949.1

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