| Type | Description |
|---|---|
| Definition | protein tyrosine phosphatase receptor type H |
| Date | Results | Publications |
|---|---|---|
| 2018-05-12 11:14:00 | The results indicate that PTPRH is downregulated in colorectal tumors and its expression is epigenetically regulated via DNA methylation and chromatin modifications. | 28713969 |
| 2016-06-04 11:19:00 | PTPRH is overexpressed in non-small cell lung cancer, is regulated by DNA hypomethylation, and PTPRH DNA methylation was an independent prognostic factor | 26134684 |
| 2010-01-21 00:00:00 | SAP-1 expression is downregulated during the dedifferentiation of human hepatocellular carcinoma, which may play a causal role in disease progression | 12879010 |
| 2010-01-21 00:00:00 | SAP-1 induces apoptotic cell death by inhibition of cell survival signaling mediated by PI 3-kinase, Akt, and ILK and activation of a caspase-dependent proapoptotic pathway. | 12101188 |
| Type | IDs |
|---|---|
| Synonymous | R-PTP-H, SAP1 |
| Gene |
UniProtKB-ID:
PTPRH_HUMAN
UniprotKB:
Q9HD43
UniParc:
UPI00016428F2,
UPI000052D443,
UPI0004438046
EMBL:
AF275141,
AF275147,
AF275132,
AF275135,
AF275149,
AF275133,
AF275146,
AF275142,
AF275139,
AC010327,
AF275148,
AF275140,
AF275145,
AF275144,
AF275150,
D15049,
AF275138,
AF275134,
AF275143,
AF275137,
BC111715,
BC111716,
AF275136,
AF275131
Ensembl:
ENSG00000080031
KO:
hsa:5794
|
| Nucleutide sequences |
EMBL-CDS:
BAA03645.2,
AAF91411.1,
AAI11717.1,
AAI11716.1
Ensembl_TRS:
ENST00000263434,
ENST00000376350
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000365528,
ENSP00000263434
RefSeq:
XP_016882553.1,
XP_016882546.1,
XP_016882545.1,
XP_011525492.1,
XP_016882552.1,
XP_011525490.1,
NP_002833.4,
XP_011525485.1,
XP_016882550.1,
XP_016882551.1,
XP_016882547.1,
NP_001154912.2,
XP_016882548.1,
XP_016882549.1
|
| Others |
UniRef100:
UniRef100_Q9HD43
UniRef90:
UniRef90_Q9HD43
UniRef50:
UniRef50_Q9HD43
UniGene:
Hs.179770,
Hs.657630
CCDS:
CCDS33110.1,
CCDS54321.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员