| Type | Description |
|---|---|
| Definition | protein tyrosine phosphatase receptor type B |
| Date | Results | Publications |
|---|---|---|
| 2021-01-09 13:30:00 | PSMD11, PTPRM and PTPRB as novel biomarkers of pancreatic cancer progression. | 32663515 |
| 2020-09-19 16:23:00 | Exploring the effect of inhibitor AKB-9778 on VE-PTP by molecular docking and molecular dynamics simulation. | 31125141 |
| 2020-06-13 11:50:00 | The search for substrates of VE-PTP revealed that proteins relevant for the regulation of endothelial junctions and of cell adhesion are over-represented among the potential targets of VE-PTP, supporting the concept that VEPTP is an important regulator of vascular integrity and junctional signaling. | 31427368 |
| 2020-05-23 13:17:00 | PTPRB overexpression decreased vimentin expression and promoted E-cadherin expression, consistent with promotion of EMT, while PTPRB knockdown had the opposite effect. | 31040266 |
| 2020-05-09 12:51:00 | Study found PTPRB negatively correlated with miR-624 expression in osteosarcoma (OS) tissues. PTPRB was confirmed as a downstream target of miR-624. | 31829261 |
| Type | IDs |
|---|---|
| Synonymous | HPTP-BETA, HPTPB, PTPB, R-PTP-BETA, VEPTP |
| Gene |
UniProtKB-ID:
PTPRB_HUMAN,
Q86VA4_HUMAN,
F8VU56_HUMAN,
Q68D73_HUMAN
UniprotKB:
P23467,
Q86VA4,
F8VU56,
Q68D73
UniParc:
UPI00001969B6,
UPI00020CE282,
UPI0002065526,
UPI000041A155,
UPI00001FC788,
UPI00002294FA,
UPI000189A7F7
EMBL:
AC025569,
AC083809,
BC143360,
BC051329,
BX648245,
X54131,
CH471054,
BC101679,
BC143356,
CR749546,
BC113463
Ensembl:
ENSG00000127329
KO:
hsa:5787
|
| Nucleutide sequences |
EMBL-CDS:
CAA38066.1,
EAW97254.1,
AAI43357.1,
AAI13464.1,
AAI43361.1,
AAI01680.1,
AAH51329.1,
CAH18347.1
Ensembl_TRS:
ENST00000261266,
ENST00000550857,
ENST00000334414,
ENST00000538708,
ENST00000550358
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000447302,
ENSP00000334928,
ENSP00000261266,
ENSP00000438927,
ENSP00000448058
RefSeq:
XP_006719592.1,
NP_001193901.1,
XP_011536916.1,
NP_001103224.1,
NP_001317133.1,
NP_002828.3,
NP_001193900.1,
XP_006719591.1,
XP_016875213.1
|
| Others |
UniRef100:
UniRef100_Q86VA4,
UniRef100_F8VU56,
UniRef100_Q68D73,
UniRef100_P23467
UniRef90:
UniRef90_H2Q6G6,
UniRef90_F8VU56,
UniRef90_P23467
UniRef50:
UniRef50_A0A2K6CA61,
UniRef50_P23467,
UniRef50_T0MK94
UniGene:
Hs.434375
CCDS:
CCDS55845.1,
CCDS44943.1,
CCDS55846.1,
CCDS44944.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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