| Type | Description |
|---|---|
| Definition | grainyhead like transcription factor 3 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-06 13:55:00 | Epidermal progenitors suppress GRHL3-mediated differentiation through intronic polyadenylation promoted by CPSF-HNRNPA3 collaboration. | 33469008 |
| 2020-08-29 10:45:00 | In the case-control study, significant associations were found between C27G genetic variants on rs2486668 and risk for spina bifida and encephalocele, respectively, under different genetic models. GG genotype on rs2486668 was associated with increased risk for spina bifida, with a RR of 2.15 (95% CI: 1.20-3.83).The GRHL3 C67G missense variant may increase the risk for spina bifida and encephalocele phenotypes. | 31332962 |
| 2019-12-14 10:15:00 | Deletion of the transcription factor GRHL3 in the skin initiates a chemokine responsive signal leading to keratinocytes hyperproliferation and a pro-tumorigenic state. | 30341279 |
| 2019-10-05 12:56:00 | We identified rare damaging variants in four genes known to be mutated in syndromic lip and/or cleft palate (syCL/P) : TP63 (one family), TBX1 (one family), LRP6 (one family) and GRHL3 (two families), and clinical reassessment confirmed the isolated nature of their lip and/or cleft palate (CL/P). | 29500247 |
| 2019-06-29 12:28:00 | Hypomethylation of GRHL3 in central nervous tissue is associated with neural tube defects. | 29587534 |
| Type | IDs |
|---|---|
| Synonymous | SOM, TFCP2L4, VWS2 |
| Gene |
UniProtKB-ID:
GRHL3_HUMAN
UniprotKB:
Q8TE85
UniParc:
UPI0000E5926C,
UPI00001E0597,
UPI00001E0596,
UPI000049DC7B,
UPI0000251E43
EMBL:
AY231161,
CH471134,
AK315164,
BC036890,
AL031431,
AY231160,
AL138902,
AK074386
Ensembl:
ENSG00000158055
KO:
hsa:57822
|
| Nucleutide sequences |
EMBL-CDS:
EAW95121.1,
BAB85067.1,
AAH36890.1,
BAG37608.1,
AAO67370.1
Ensembl_TRS:
ENST00000356046,
ENST00000361548,
ENST00000236255,
ENST00000350501
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000348333,
ENSP00000288955,
ENSP00000236255,
ENSP00000354943
RefSeq:
XP_011540172.1,
NP_001181939.1,
NP_937816.1,
XP_011540171.1,
NP_067003.2,
NP_937817.3
|
| Others |
UniRef100:
UniRef100_Q8TE85
UniRef90:
UniRef90_Q8TE85
UniRef50:
UniRef50_Q8TE85
UniGene:
Hs.657920
CCDS:
CCDS252.2,
CCDS44088.1,
CCDS251.1,
CCDS53284.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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