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57818 G6PC2

57818

G6PC2

glucose-6-phosphatase catalytic subunit 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition glucose-6-phosphatase catalytic subunit 2

研究结论

Date Results Publications
2018-11-10 12:03:00 The results suggest that the GCKR and G6PC2 genes may contribute to the risk of type 2 diabetes independently and/or in an interactive manner in the Han Chinese population. 30055620
2017-10-28 12:00:00 The variant in TCF7L2 that increases fasting glucose levels increases between-subject variance, whereas variants in GCK and G6PC2 that increase fasting glucose levels decrease between-subject variance. 28783164
2017-09-30 10:36:00 All three allele variants of G6PC2 (rs560887, rs16856187 and rs573225) are associated with elevated fasting glucose, with two variants (rs560887 in the Caucasians subgroup and rs16856187 under the allele and dominant model) being associated with T2 diabetes as well.[meta-analysis] 28704540
2017-08-12 11:46:00 these studies identify multiple G6PC2 variants that have the potential to be associated with altered FBG in humans. 27611587
2016-03-19 10:19:00 Data suggest that islet-specific glucose 6 phosphatase catalytic subunit-related protein (IGRP)-specific CD4(+) helper T (Th) cells play a unique pathogenic role in adult-onset T1D (AT1D). 26341315

名称对应

Type IDs
Synonymous IGRP
Gene
UniProtKB-ID: G6PC2_HUMAN
UniprotKB: Q9NQR9
UniParc: UPI0000F2ADE1, UPI0000401FD8, UPI0000048D51
EMBL: CR627438, BC113376, BQ777188, CH471058, AF283835, BC104778, AC069137
Ensembl: ENSG00000278373, ENSG00000152254
KO: hsa:57818
Nucleutide sequences
EMBL-CDS: AAI13377.1, EAX11291.1, AAF82810.1, AAI04779.1, CAH10524.1
Ensembl_TRS: ENST00000429379, ENST00000375363, ENST00000617403, ENST00000622133, ENST00000282075, ENST00000612807
Protein sequencees
Ensembl_PRO: ENSP00000282075, ENSP00000396939, ENSP00000483899, ENSP00000364512, ENSP00000482583, ENSP00000481098
RefSeq: XP_011509867.1, XP_011509866.1, NP_001075155.1, NP_066999.1
Others
UniRef100: UniRef100_Q9NQR9
UniRef90: UniRef90_Q9NQR9
UniRef50: UniRef50_Q9NQR9
UniGene: Hs.283963
CCDS: CCDS2230.1, CCDS46443.1

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