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57814 Kcne4

57814

Kcne4

potassium voltage-gated channel, Isk-related subfamily, gene 4

protein-coding

Mus musculus

基因描述

Type Description
Definition potassium voltage-gated channel, Isk-related subfamily, gene 4

研究结论

Date Results Publications
2020-05-23 10:50:00 experimental data and the in silico structure suggest that the KCNE4 interaction hides a forward-trafficking motif within Kv1.3 in addition to adding a strong endoplasmic reticulum retention signature to the Kv1.3-KCNE4 complex. 30969795
2020-02-22 11:40:00 Kcne4 deletion sex dependently exacerbates hepatic ischemia-reperfusion injury, by RISK/SAFE pathway induction. 30758982
2019-11-30 12:56:00 this study show that Kcne4 deletion sex-specifically predisposes to cardiac arrhythmia via testosterone-dependent impairment of RISK/SAFE pathway induction in aged mice 29844497
2017-08-05 10:56:00 the tertiary structure of the C-terminal domain of Kv1.3 is necessary and sufficient for Kv1.3- KCNE4 interaction. 27802162
2017-05-13 10:59:00 Suggest role for KCNE4 in regulation of Kv7 channel activity to modulate vascular tone, and provide the first known molecular mechanism for sex-specificity of this modulation. 27710966

名称对应

Type IDs
Synonymous AW487937, MiRP3
Gene
UniProtKB-ID: KCNE4_MOUSE
UniprotKB: Q9WTW3
UniParc: UPI0000023C3A
EMBL: BC032920, AF076533
Ensembl: ENSMUSG00000047330
KO: mmu:57814
Nucleutide sequences
EMBL-CDS: AAD28091.1, AAH32920.1
Ensembl_TRS: ENSMUST00000057262
Protein sequencees
Ensembl_PRO: ENSMUSP00000055415
RefSeq: NP_067317.1
Others
UniRef100: UniRef100_Q9WTW3
UniRef90: UniRef90_Q9WTW3
UniRef50: UniRef50_Q9WTW3
UniGene: Mm.24386
CCDS: CCDS15088.1

全选

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研究热度

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