| Type | Description |
|---|---|
| Definition | DNA polymerase delta 4, accessory subunit |
| Date | Results | Publications |
|---|---|---|
| 2020-03-28 10:03:00 | The role in cellular processes (DNA replication, DNA repair, homologous recombination) and cell cycle regulation of 2 forms of human DNA polymerase delta: delta3 and delta4 was reviewed. (REVIEW) | 31326365 |
| 2020-02-29 11:06:00 | Human Poldelta is a pentameric complex with a dimeric p12 subunit. RKR-mediated dimerization plays a vital role in p12 binding to PCNA and Poldelta5 architecture, and the phenomenon appears to be conserved throughout evolution. | 30885984 |
| 2015-06-20 10:30:00 | the p12/Pol delta is a target as a nuclear substrate of mu-calpain in a calcium-triggered apoptosis and appears to be a potential marker in the study of the chemotherapy of cancer therapies. | 24691096 |
| 2014-09-06 10:17:00 | A parallel study of Pol delta4 and Pol delta3 in Okazaki fragment processing provides evidence for a role of Pol delta3 in DNA replication | 24300032 |
| 2014-06-21 13:04:00 | Findings provide evidence for the novel concept that Pol delta3 has a role in lagging strand synthesis, and that both forms of Pol delta3 and 4 may participate in DNA replication in higher eukaryotic cells. | 24035200 |
| Type | IDs |
|---|---|
| Synonymous | POLDS, p12 |
| Gene |
UniProtKB-ID:
DPOD4_HUMAN,
A0A024R5D7_HUMAN,
Q6NSD7_HUMAN
UniprotKB:
Q9HCU8,
A0A024R5D7,
Q6NSD7
UniParc:
UPI000035ECC3,
UPI0000129741,
UPI0001EE47C1
EMBL:
BC070250,
BG403692,
CH471076,
AP003419,
AF179890,
AY928482
Ensembl:
ENSG00000175482
KO:
hsa:57804
|
| Nucleutide sequences |
EMBL-CDS:
AAG08966.1,
AAX09676.1,
EAW74600.1,
EAW74598.1,
AAH70250.1
Gene_ORFName:
hCG_1639765
Ensembl_TRS:
ENST00000312419,
ENST00000539074
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000311368,
ENSP00000444780
RefSeq:
NP_066996.3,
NP_001243799.1
|
| Others |
UniRef100:
UniRef100_Q6NSD7,
UniRef100_Q9HCU8
UniRef90:
UniRef90_Q9HCU8,
UniRef90_Q6NSD7
UniRef50:
UniRef50_Q6NSD7,
UniRef50_Q9HCU8
UniGene:
Hs.523829
CCDS:
CCDS8158.1,
CCDS58149.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员