| Type | Description |
|---|---|
| Definition | TNFAIP3 interacting protein 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-10-03 10:34:00 | The ABIN-1 heterozygosity sensitizes innate immune response of Abin-1(+/)(-) mice in vivo by promoting the production of proinflammatory cytokines, which can be blocked upon inhibition of RIPK1 kinase. | 30341420 |
| 2020-07-25 11:54:00 | The splenic iMo of ABIN1[D485N] mice displayed high expression of mRNAs encoding proteins controlling cell division and were actively dividing; this may underlie the increased pMo and MoDC numbers, which are derived from iMo. | 31694920 |
| 2019-06-29 10:08:00 | These data show that the disease susceptibility proteins A20 and ABIN-1 synergistically prevent intestinal inflammation by restricting IEC death and preserving tissue integrity. | 29930103 |
| 2019-04-06 12:39:00 | It has been proposed that ABIN-1 provides a critical link between methionine1 ubiquitylation mediated by the LUBAC complex and lysine63 deubiquitylation by phospho-A20 to modulate the activation of RIPK1. | 29203883 |
| 2018-10-13 10:18:00 | Reduced expression of TNIP1 was determined in hepatic ischemia/reperfusion (I/R) injury compared to normal mice. Then, TNIP1 transgene mice were used to determine the effects of TNIP1 on mice after treatment for I/R. | 29709475 |
| Type | IDs |
|---|---|
| Synonymous | ABIN, ABIN-1, ABIN1, AU018810, Naf1, Nef, VAN |
| Gene |
UniProtKB-ID:
TNIP1_MOUSE,
D3Z2W0_MOUSE,
E9QM75_MOUSE
UniprotKB:
Q9WUU8,
D3Z2W0,
E9QM75
UniParc:
UPI000059DC5E,
UPI0000D77A73,
UPI000002AEC3,
UPI0000028F29,
UPI000002AEC2
EMBL:
BC008186,
AJ242778,
AX011241,
BC008665,
AY012159,
AJ242777,
AL593846
Ensembl:
ENSMUSG00000020400
KO:
mmu:57783
|
| Nucleutide sequences |
EMBL-CDS:
CAB44239.1,
AAH08665.1,
AAG42155.2,
AAH08186.1,
CAB44240.1,
CAC07546.1
Ensembl_TRS:
ENSMUST00000108885,
ENSMUST00000108886,
ENSMUST00000102730,
ENSMUST00000108889,
ENSMUST00000102731,
ENSMUST00000018482
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000104513,
ENSMUSP00000104514,
ENSMUSP00000099791,
ENSMUSP00000099792,
ENSMUSP00000018482,
ENSMUSP00000104517
RefSeq:
XP_006533910.1,
NP_001186204.1,
XP_006533909.1,
NP_001258385.1,
XP_030102057.1,
XP_011247465.1,
XP_006533911.1,
XP_011247466.1,
NP_067302.2,
NP_001186205.1,
XP_030102059.1,
XP_030102056.1,
NP_001258384.1,
XP_011247464.1
|
| Others |
UniRef100:
UniRef100_D3Z2W0,
UniRef100_Q9WUU8,
UniRef100_E9QM75
UniRef90:
UniRef90_Q9WUU8
UniRef50:
UniRef50_Q15025
UniGene:
Mm.259671
CCDS:
CCDS56769.1,
CCDS70188.1,
CCDS24704.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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