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5778 PTPN7

5778

PTPN7

protein tyrosine phosphatase non-receptor type 7

protein-coding

Homo sapiens

基因描述

Type Description
Definition protein tyrosine phosphatase non-receptor type 7

研究结论

Date Results Publications
2020-03-28 10:47:00 PTPN7 regulates platelet functional responses downstream of GPCR agonists, but not GPVI agonists, through inhibition of ERK activation and thromboxane generation. 31266805
2010-09-15 22:06:00 Observational study and genome-wide association study of gene-disease association. (HuGE Navigator) 20668459
2010-01-21 00:00:00 structure of the protein tyrosine phosphatase catalytic domain of HePTP, residues 44-339 16226275
2010-01-21 00:00:00 Interactions at the active site between KIM (kinase interaction motif)-phosphatases and their substrates are predominantly nonspecific, with the majority of the KIM-phosphatase residues coordinating the peptide backbone rather than residue side chains. 19053285
2010-01-21 00:00:00 determined high-resolution structures of all of the human family members of Mitogen-Activated protein tyrosine phosphatases 16441242

名称对应

Type IDs
Synonymous BPTP-4, HEPTP, LC-PTP, LPTP, PTPNI
Gene
UniProtKB-ID: PTN7_HUMAN, A0A024R9A7_HUMAN, B4DZD9_HUMAN
UniprotKB: P35236, A0A024R9A7, B4DZD9
UniParc: UPI00017A831F, UPI000013296B, UPI000013EE09, UPI00004701F6
EMBL: BC001746, D11327, M64322, AK302869, CH471067, AK127214, AL592300, BT009848
Ensembl: ENSG00000143851
KO: hsa:5778
Nucleutide sequences
EMBL-CDS: BAA01946.1, AAP88850.1, AAA59531.1, BAG54453.1, AAH01746.2, EAW91405.1, EAW91404.1, BAG64051.1
Gene_ORFName: hCG_31786
Ensembl_TRS: ENST00000495688, ENST00000367279, ENST00000309017
Protein sequencees
Ensembl_PRO: ENSP00000356248, ENSP00000420506, ENSP00000309116
RefSeq: XP_011508123.1, NP_542155.1, XP_011508126.1, NP_001186726.1, NP_002823.4, XP_011508122.1, NP_001351807.1, XP_011508124.1, XP_024304479.1, XP_011508125.1, XP_016857425.1, NP_001351806.1, XP_016857424.1, XP_011508121.1
Others
UniRef100: UniRef100_P35236, UniRef100_A0A024R9A7, UniRef100_B4DZD9
UniRef90: UniRef90_P35236, UniRef90_B4DZD9, UniRef90_A0A2K6PAY3
UniRef50: UniRef50_A0A4X2K2D8, UniRef50_P35236
UniGene: Hs.402773
CCDS: CCDS1422.1, CCDS1423.2

全选

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