| Type | Description |
|---|---|
| Definition | formin-like 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-13 13:20:00 | Formin-like 1 mediates effector T cell trafficking to inflammatory sites to enable T cell-mediated autoimmunity. | 32510333 |
| 2018-12-22 10:12:00 | FMNL1 is required for actin assembly on lipid droplets (LDs) in vitro and for NMIIa recruitment to LDs in cells. We propose a novel acto-myosin structure regulating lipid storage: FMNL1-dependent assembly of myosin II-functionalized actin filaments on LDs facilitates their dissociation, thereby affecting LD surface-to-volume ratio and enzyme accessibility to triglycerides. | 28361956 |
| 2016-06-28 10:43:00 | In oocyte meiosis, FMNL1 is required for spindle organization and actin assembly. | 26083584 |
| 2015-04-25 11:33:00 | Depleting FMNL1, another Formin family member, resulted in reduced mDia1 expression, while RhoA inhibition did not alter mDia1 expression, which indicated that there was a FMNL1-mDia1-Profilin1 signaling pathway in mouse oocytes. | 25447542 |
| 2014-11-08 11:15:00 | FMNL1 and FMNL2 are required non-redundantly in the repair of damaged myofibrils. | 24430873 |
| Type | IDs |
|---|---|
| Synonymous | 8030453N10Rik, AI553564, Fmnl, Fnrl, Frls |
| Gene |
UniProtKB-ID:
FMNL1_MOUSE,
A0A1W2P6X3_MOUSE,
A2AB60_MOUSE,
Q3TY82_MOUSE
UniprotKB:
Q9JL26,
A0A1W2P6X3,
A2AB60,
Q3TY82
UniParc:
UPI000051AE85,
UPI0003D715B8,
UPI00005AD235,
UPI0000028B8C,
UPI000059DD4D
EMBL:
AF006466,
AF215666,
AK131173,
AK158820,
AL662804
Ensembl:
ENSMUSG00000055805
KO:
mmu:57778
|
| Nucleutide sequences |
EMBL-CDS:
BAD21423.1,
AAF25953.1,
AAD01273.1,
BAE34681.1
Ensembl_TRS:
ENSMUST00000042286,
ENSMUST00000218163,
ENSMUST00000107027
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000046296,
ENSMUSP00000151439,
ENSMUSP00000102642
RefSeq:
XP_006533906.1,
XP_006533908.1,
XP_006533904.1,
XP_006533905.1,
XP_006533902.1,
XP_006533900.1,
XP_036012763.1,
NP_062653.2,
XP_006533907.1,
XP_006533903.1,
XP_006533901.1,
NP_001071166.1
|
| Others |
UniRef100:
UniRef100_A0A1W2P6X3,
UniRef100_Q9JL26,
UniRef100_Q3TY82,
UniRef100_A2AB60
UniRef90:
UniRef90_Q3TY82,
UniRef90_A0A0G2JYU6,
UniRef90_Q9JL26
UniRef50:
UniRef50_A0A1A8EV29,
UniRef50_O95466
UniGene:
Mm.138913
CCDS:
CCDS36348.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员