| Type | Description |
|---|---|
| Definition | nuclear receptor coactivator 5 |
| Date | Results | Publications |
|---|---|---|
| 2020-06-27 12:09:00 | Results found the expression levels of NCOA5 mRNA and protein significantly decreased in cervical cancer (CC) tissues and correlated with poor overall survival. Its upregulation might suppress cancer cell proliferation, migration, and invasion by inactivating NOTCH3 signaling pathway. These findings suggest that NCOA5 acts as a tumor suppressor and represents a potential novel prognostic marker for overall survival in CC. | 30335900 |
| 2018-09-22 11:09:00 | knockout of NCOA5 can suppress the epithelial - mesenchymal transition (EMT) in hepatocellular carcinoma cells. | 29626478 |
| 2017-05-27 10:26:00 | This study provides new insights and evidences that NOCA5 over-expression was significantly correlated with progression and prognosis in luminal breast cancer. However, the precise cellular mechanisms for NOCA5 in luminal breast cancer need to be further explored. | 27847318 |
| 2015-10-31 11:04:00 | NCOA5 low expression correlates with survival in esophageal squamous cell carcinoma. | 25416054 |
| 2014-02-15 11:58:00 | suggest that NCOA5 is a haploinsufficient tumor suppressor and that NCOA5 deficiency increases susceptibility to both glucose intolerance and HCC, partially by increasing IL-6 expression | 24332041 |
| Type | IDs |
|---|---|
| Synonymous | CIA, bA465L10.6 |
| Gene |
UniProtKB-ID:
NCOA5_HUMAN
UniprotKB:
Q9HCD5
UniParc:
UPI000000D7B2
EMBL:
AF470686,
CH471077,
BC140836,
AF230533,
AB046857,
BC151133,
AL162458,
AL035662
Ensembl:
ENSG00000124160
KO:
hsa:57727
|
| Nucleutide sequences |
EMBL-CDS:
AAI51134.1,
AAG36793.1,
EAW75765.1,
EAW75769.1,
AAO33457.1,
BAB13463.1,
AAI40837.1
Ensembl_TRS:
ENST00000290231
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000290231
RefSeq:
NP_066018.1,
NP_001335078.1,
NP_001335079.1,
NP_001335080.1,
NP_001335077.1
|
| Others |
UniRef100:
UniRef100_Q9HCD5
UniRef90:
UniRef90_Q9HCD5
UniRef50:
UniRef50_Q9HCD5
UniGene:
Hs.654991
CCDS:
CCDS13392.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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