例如:"NBL1", "4681", "drought"
收藏
57697 FANCM

57697

FANCM

FA complementation group M

protein-coding

Homo sapiens

基因描述

Type Description
Definition FA complementation group M

研究结论

Date Results Publications
2020-12-05 13:02:00 FANCM suppresses DNA replication stress at ALT telomeres by disrupting TERRA R-loops. 31836759
2020-09-26 13:09:00 DONSON and FANCM associate with different replisomes distinguished by replication timing and chromatin domain. 32769987
2020-07-04 10:54:00 Following introduction of genomic interstrand crosslinks and dependent on ATR and FANCD2 but not on the Fanconi anemia core proteins or FAAP24, FANCM binds the replisome complex. 31067464
2020-05-16 10:42:00 The expression and activity of FANCM, a DNA translocase protein, is essential for the viability of Alternative Lengthening of Telomeres (ALT)-associated cancers. 31663812
2019-12-07 11:41:00 FANCM is a tumor suppressor gene that encodes a conserved and structure-specific DNA translocase. [review] 30714416

名称对应

Type IDs
Synonymous FAAP250, KIAA1596, POF15, SPGF28
Gene
UniProtKB-ID: FANCM_HUMAN
UniprotKB: Q8IYD8
UniParc: UPI000007427A, UPI0001747A05, UPI000059F032
EMBL: AK093422, DQ140356, AL121809, BC036056, BC144511, AB046816, BC140776
Ensembl: ENSG00000187790
KO: hsa:57697
Nucleutide sequences
EMBL-CDS: AAI44512.1, AAI40777.1, BAC04159.1, AAZ53290.1, AAH36056.1, BAB13422.1
Ensembl_TRS: ENST00000542564, ENST00000556036, ENST00000267430
Protein sequencees
Ensembl_PRO: ENSP00000267430, ENSP00000442493, ENSP00000450596
RefSeq: XP_016877015.1, XP_011535337.1, NP_065988.1, XP_016877013.1, XP_016877012.1, XP_011535336.1, NP_001295062.1, XP_011535339.1, XP_016877016.1, NP_001295063.1, XP_016877014.1
Others
UniRef100: UniRef100_Q8IYD8
UniRef90: UniRef90_Q8IYD8
UniRef50: UniRef50_Q8IYD8
UniGene: Hs.509229
CCDS: CCDS76677.1, CCDS32070.1, CCDS81802.1

全选

{{proteinIndex+1}}
mRNA Protein UniprotKB Description
Refseq {{protein.nucleotideVersion}}

Ensembl: {{protein.nucleotideEnsembl}}

{{protein.proteinVersion}}

Ensembl: {{protein.proteinEnsembl}}

{{uniprot}}
Definition: {{{protein.definition}}}

Transcript Veriant:{{protein.transcriptVeriant}}

Status: {{protein.status}}

Location ( {{protein.positionStart}}..{{protein.positionEnd}} )

暂无数据

研究热度

热点单位
排名 科研单位 文献
{{affIndex+1}}

{{aff.value}}

{{aff.size}}

目前还没有研究热点单位

热点人员
排名 研究人员 文献
{{authorIndex+1}}

{{author.value}}

{{author.size}}

目前还没有研究热点人员