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5768 QSOX1

5768

QSOX1

quiescin sulfhydryl oxidase 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition quiescin sulfhydryl oxidase 1

研究结论

Date Results Publications
2021-03-20 13:29:00 QSOX1 promotes mitochondrial apoptosis of hepatocellular carcinoma cells during anchorage-independent growth by inhibiting lipid synthesis. 32863002
2020-01-25 14:06:00 Hypoxia-induced upregulation of QSOX1 and a consequent elevation in intracellular H2O2 increased apoptosis in placentae of pregnancies complicated by Preeclampsia. 29712536
2020-01-25 13:34:00 mutation of a conserved cis-proline amino acid, analogous to a mutation used to trap substrates of a bacterial disulfide catalyst, has a dramatic effect on the physiological function of the mammalian disulfide catalyst QSOX1. 30367560
2019-02-02 10:33:00 QSOX1 might be a lung cancer tissue-derived biomarker and be involved in the promotion of lung cancers, and thus can be a therapeutic target for lung cancers. 30336636
2018-12-22 10:28:00 This study provides a key example of the effect of glycosylation on Golgi exit and contributes to an understanding of late secretory sorting and quality control. 29757379

名称对应

Type IDs
Synonymous Q6, QSCN6
Gene
UniProtKB-ID: QSOX1_HUMAN, Q13876_HUMAN, A0A140VKE5_HUMAN
UniprotKB: O00391, Q13876, A0A140VKE5
UniParc: UPI000007136A, UPI000014D53D, UPI000004C63C
EMBL: AY358941, HM005685, BC017692, AL390718, U97276, AB209280, L42379, AF361868, BC100023, CH471067
Ensembl: ENSG00000116260
KO: hsa:5768
Nucleutide sequences
EMBL-CDS: AAI00024.1, AAC09010.2, BAD92517.1, AAM00263.1, AAH17692.1, AAQ89300.1, AAA89173.1, AEE61282.1, EAW91077.1
Gene_ORFName: UNQ2520/PRO6013, hCG_22650
Ensembl_TRS: ENST00000367602, ENST00000367600
Protein sequencees
Ensembl_PRO: ENSP00000356574, ENSP00000356572
RefSeq: NP_001004128.1, NP_002817.2
Others
UniRef100: UniRef100_Q13876, UniRef100_A0A140VKE5, UniRef100_O00391
UniRef90: UniRef90_A0A140VKE5, UniRef90_Q13876, UniRef90_O00391
UniRef50: UniRef50_Q8BND5, UniRef50_O00391
UniGene: Hs.744925
CCDS: CCDS1337.1, CCDS30950.1

全选

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