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57659 ZBTB4

57659

ZBTB4

zinc finger and BTB domain containing 4

protein-coding

Homo sapiens

基因描述

Type Description
Definition zinc finger and BTB domain containing 4

研究结论

Date Results Publications
2020-04-04 11:13:00 miR-301-3p was highly expressed in gastric cancer contributed to tumor progression via attenuating ZBTB4 31585814
2018-11-10 10:43:00 Results show association between AAO of AD and both ZBTB4 and NCSTN. ZBTB4 is a transcriptional repressor that regulates the cell cycle, including the apoptotic response to amyloid beta, while NCSTN is part of the gamma secretase complex, known to influence amyloid beta production. 29045054
2018-09-08 11:56:00 In vitro, ZBTB4 overexpression inhibited cell proliferation, and induced cell cycle arrest at G1 phase and apoptosis in SK-ES-1 and RD-ES cells. 29425745
2017-07-29 10:10:00 Our results establish the epigenetic regulator ZBTB4 as an essential component in maintaining genomic stability 27815388
2015-08-22 11:16:00 Thus, EZH2 is reciprocally regulated by a novel signaling network consisting of Sp proteins, oncogenic miRs and ZBTB4, and modulation of this gene network is a novel therapeutic approach for treatment of breast cancer and possibly other cancers. 25499219

名称对应

Type IDs
Synonymous KAISO-L1, ZNF903
Gene
UniProtKB-ID: ZBTB4_HUMAN, B3KVD4_HUMAN
UniprotKB: Q9P1Z0, B3KVD4
UniParc: UPI000178E02E, UPI00001A9C9A
EMBL: BC033259, AK122971, BC043352, AY302699, AB040971, AK122826, CH471108
Ensembl: ENSG00000174282, ENSG00000283868
KO: hsa:57659
Nucleutide sequences
EMBL-CDS: EAW90185.1, AAH43352.1, BAA96062.2, AAH33259.1, BAG53828.1, AAP59447.1, BAG53746.1
Ensembl_TRS: ENST00000380599, ENST00000639670, ENST00000639962, ENST00000311403
Protein sequencees
Ensembl_PRO: ENSP00000492616, ENSP00000369973, ENSP00000492232, ENSP00000307858
RefSeq: XP_006721626.1, XP_011522274.1, XP_006721627.1, NP_065950.2, NP_001122305.1
Others
UniRef100: UniRef100_Q9P1Z0
UniRef90: UniRef90_Q9P1Z0
UniRef50: UniRef50_Q9P1Z0
UniGene: Hs.35096
CCDS: CCDS11107.1

全选

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