| Type | Description |
|---|---|
| Definition | GRAM domain containing 1A |
| Date | Results | Publications |
|---|---|---|
| 2019-07-20 10:09:00 | GRAMD2a, but not GRAMD1a, co-localizes with the E-Syt2/3 tethers at endoplasmic reticulum-plasma membrane contact sites in a phosphatidylinositol phosphate lipid-dependent manner. Data from an analysis of cells lacking GRAMD2a suggest that it is an organizer of the membrane contact sites with pleiotropic functions including calcium homeostasis. | 29469807 |
| 2018-06-02 11:48:00 | was the target of GRAMD1A; GRAMD1A regulated the target genes of duanyu18135 and the transcriptional activity of Inhibition of duanyu18135 in indicated HCC cells overexpressing GRAMD1A suppressed the effects of GRAMD1A on the self-renewal of HCC stem cell, resistance to chemotherapy and tumor growth, suggesting GRAMD1A promoted the self-renewal of HCC stem cells and the development of HCC by increasing duanyu18135 level. | 27585821 |
| Type | IDs |
|---|---|
| Synonymous | KIAA1533 |
| Gene |
UniProtKB-ID:
ASTRA_HUMAN,
M0QZ12_HUMAN,
B3KUH3_HUMAN,
B3KQF7_HUMAN
UniprotKB:
Q96CP6,
M0QZ12,
B3KUH3,
B3KQF7
UniParc:
UPI000015D8F3,
UPI000150AEEB,
UPI0000202095,
UPI00000377B4,
UPI000059D6DF,
UPI0000373225
EMBL:
AC020907,
AB040966,
AK097215,
BC014077,
AK074864,
AK074914
Ensembl:
ENSG00000089351
KO:
hsa:57655
|
| Nucleutide sequences |
EMBL-CDS:
BAA96057.1,
BAC11289.1,
AAH14077.2,
BAG53435.1,
BAG52019.1
Ensembl_TRS:
ENST00000411896,
ENST00000317991,
ENST00000599564
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000439267,
ENSP00000441032,
ENSP00000470220
RefSeq:
XP_011525455.1,
XP_011525458.1,
XP_016882524.1,
NP_065946.2,
XP_011525451.1,
XP_024307391.1,
XP_011525456.1,
NP_001129671.1,
NP_001306964.1,
XP_011525457.1,
NP_001306963.1,
XP_016882523.1,
NP_001306965.1,
XP_024307390.1
|
| Others |
UniRef100:
UniRef100_M0QZ12,
UniRef100_B3KUH3,
UniRef100_Q96CP6,
UniRef100_B3KQF7
UniRef90:
UniRef90_Q96CP6,
UniRef90_A0A2I3HVY8,
UniRef90_B3KUH3,
UniRef90_B3KQF7
UniRef50:
UniRef50_A0A1S3WWU6,
UniRef50_Q8VEF1
UniGene:
Hs.515351
CCDS:
CCDS46046.1,
CCDS42546.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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