| Type | Description |
|---|---|
| Definition | myosin heavy chain 7B |
| Date | Results | Publications |
|---|---|---|
| 2017-12-30 10:15:00 | The actin-based motor myosin-7b (Myo7b) promotes the accumulation of intermicrovillar adhesion complex (IMAC components at microvillar tips. Myo7b is highly enriched at the tips of microvilli in both kidney and intestinal brush borders, and loss of Myo7b in differentiating intestinal epithelial cells disrupts intermicrovillar adhesion and, thus, brush border assembly. | 27666969 |
| 2014-01-04 12:39:00 | Digenic mutational inheritance of the integrin alpha 7 and the myosin heavy chain 7B genes causes congenital myopathy with left ventricular non-compact cardiomyopathy. [MYH7B] | 23800289 |
| 2010-09-15 22:06:00 | Observational study of gene-disease association. (HuGE Navigator) | 19913121 |
| 2010-09-15 22:06:00 | Observational study of gene-disease association. (HuGE Navigator) | 20224305 |
| 2010-09-15 22:06:00 | Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) | 20628086 |
| Type | IDs |
|---|---|
| Synonymous | MHC14, MYH14 |
| Gene |
UniProtKB-ID:
MYH7B_HUMAN
UniprotKB:
A7E2Y1
UniParc:
UPI000046D367,
UPI00017BE791,
UPI000006F64E
EMBL:
BC007808,
BC069406,
BC151242,
KF456882,
AY288964,
CH471077,
AL133324,
AL132825,
BC069327,
AB040945,
AK000947
Ensembl:
ENSG00000078814
KO:
hsa:57644
|
| Nucleutide sequences |
EMBL-CDS:
AAI51243.1,
AAQ93060.1,
AAH69406.2,
EAW76237.1,
AAH69327.2,
AAH07808.1,
BAA91440.1,
BAA96036.2
Ensembl_TRS:
ENST00000618182
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000483640
RefSeq:
XP_011527249.1,
NP_065935.3,
XP_006723903.1,
XP_011527250.1,
XP_011527243.1,
XP_016883475.1
|
| Others |
UniRef100:
UniRef100_A7E2Y1
UniRef90:
UniRef90_A7E2Y1
UniRef50:
UniRef50_A7E2Y1
UniGene:
Hs.414122
CCDS:
CCDS42869.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 32296183 |
A reference map of the human binary protein interactome. Nature Katja Luck , Dae-Kyum Kim , Luke Lambourne , Kerstin Spirohn , Bridget E Begg , Wenting Bian , Ruth Brignall , Tiziana Cafarelli , Francisco J Campos-Laborie , Benoit Charloteaux , Dongsic Choi , Atina G Coté , Meaghan Daley , Steven Deimling , Alice Desbuleux , Amélie Dricot , Marinella Gebbia , Madeleine F Hardy , Nishka Kishore , Jennifer J Knapp , István A Kovács , Irma Lemmens , Miles W Mee , Joseph C Mellor , Carl Pollis , Carles Pons , Aaron D Richardson , Sadie Schlabach , Bridget Teeking , Anupama Yadav , Mariana Babor , Dawit Balcha , Omer Basha , Christian Bowman-Colin , Suet-Feung Chin , Soon Gang Choi , Claudia Colabella , Georges Coppin , Cassandra D'Amata , David De Ridder , Steffi De Rouck , Miquel Duran-Frigola , Hanane Ennajdaoui , Florian Goebels , Liana Goehring , Anjali Gopal , Ghazal Haddad , Elodie Hatchi , Mohamed Helmy , Yves Jacob , Yoseph Kassa , Serena Landini , Roujia Li , Natascha van Lieshout , Andrew MacWilliams , Dylan Markey , Joseph N Paulson , Sudharshan Rangarajan , John Rasla , Ashyad Rayhan , Thomas Rolland , Adriana San-Miguel , Yun Shen , Dayag Sheykhkarimli , Gloria M Sheynkman , Eyal Simonovsky , Murat TaÅan , Alexander Tejeda , Vincent Tropepe , Jean-Claude Twizere , Yang Wang , Robert J Weatheritt , Jochen Weile , Yu Xia , Xinping Yang , Esti Yeger-Lotem , Quan Zhong , Patrick Aloy , Gary D Bader , Javier De Las Rivas , Suzanne Gaudet , Tong Hao , Janusz Rak , Jan Tavernier , David E Hill , Marc Vidal , Frederick P Roth , Michael A Calderwood |
2020-04-01 | - |
| 30021884 |
Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei. Mol Cell Proteomics Domenico Fasci , Hugo van Ingen , Richard A Scheltema , Albert J R Heck |
2018-10-01 | - |
| 28514442 |
Architecture of the human interactome defines protein communities and disease networks. Nature Edward L Huttlin , Raphael J Bruckner , Joao A Paulo , Joe R Cannon , Lily Ting , Kurt Baltier , Greg Colby , Fana Gebreab , Melanie P Gygi , Hannah Parzen , John Szpyt , Stanley Tam , Gabriela Zarraga , Laura Pontano-Vaites , Sharan Swarup , Anne E White , Devin K Schweppe , Ramin Rad , Brian K Erickson , Robert A Obar , K G Guruharsha , Kejie Li , Spyros Artavanis-Tsakonas , Steven P Gygi , J Wade Harper |
2017-05-25 | - |
| 27666969 |
Myosin-7b Promotes Distal Tip Localization of the Intermicrovillar Adhesion Complex. Curr. Biol. Meredith L Weck , Scott W Crawley , Colin R Stone , Matthew J Tyska |
2016-10-24 | - |
| 26618866 |
âF508 CFTR interactome remodelling promotes rescue of cystic fibrosis. Nature Sandra Pankow , Casimir Bamberger , Diego Calzolari , Salvador MartÃnez-Bartolomé , Mathieu Lavallée-Adam , William E Balch , John R Yates |
2015-12-24 |
CFTR
|
| 26496610 |
A human interactome in three quantitative dimensions organized by stoichiometries and abundances. Cell Marco Y Hein , Nina C Hubner , Ina Poser , Jürgen Cox , Nagarjuna Nagaraj , Yusuke Toyoda , Igor A Gak , Ina Weisswange , Jörg Mansfeld , Frank Buchholz , Anthony A Hyman , Matthias Mann |
2015-10-22 |
Cep85l,
Rcc1,
Zbtb48,
Bsdc1,
Kifc1,
Ccp110,
Ints4,
Slc6a8,
Cenpi,
Nup107,
Xpo1,
Fbxw11,
Tubg1,
Csnk1d,
Bap1,
Ptpn23,
Tecpr2,
Slain1,
Ankrd28,
Prkaa1,
Espl1,
Gbf1,
Cdc20,
Cenpf,
Trip11,
Mbd5,
Kif22,
Dut,
Srsf1,
Actb,
Spred2,
Akt2,
Mta1,
Tgs1,
Pip4k2c,
Ankfy1,
Apc,
Ar,
Rhoa,
Atp2a2,
Atp5a1,
Atp7a,
Cep131,
Bach1,
Bcl7c,
Bmpr1a,
Brca1,
Bub1,
Bub1b,
C1qbp,
Anxa2,
Calu,
Cbx1,
Cbx4,
Cct2,
Cct3,
Cct4,
Cct7,
Cct8,
Cd2ap,
Cdk1,
Cdc37,
Cdh1,
Chek1,
Cit,
Copa,
Crebbp,
Cry1,
Csk,
Smc3,
Dctn1,
Ddb1,
Cdk2ap1,
Mapre1,
Ect2,
Eef1a1,
Eif3a,
Mark2,
Evpl,
Ewsr1,
Wdr5,
Dclre1b,
Fbl,
Fgfr1,
Flot1,
Flot2,
B4galt1,
Gnb1,
Gspt1,
Hdac6,
Herc2,
Hsf1,
Hsph1,
Elavl1,
Id2,
Cyr61,
Cep250,
Insr,
Eif3e
|
| 26344197 |
Panorama of ancient metazoan macromolecular complexes. Nature Cuihong Wan , Blake Borgeson , Sadhna Phanse , Fan Tu , Kevin Drew , Greg Clark , Xuejian Xiong , Olga Kagan , Julian Kwan , Alexandr Bezginov , Kyle Chessman , Swati Pal , Graham Cromar , Ophelia Papoulas , Zuyao Ni , Daniel R Boutz , Snejana Stoilova , Pierre C Havugimana , Xinghua Guo , Ramy H Malty , Mihail Sarov , Jack Greenblatt , Mohan Babu , W Brent Derry , Elisabeth R Tillier , John B Wallingford , John Parkinson , Edward M Marcotte , Andrew Emili |
2015-09-17 |
AKT3,
MED6,
ABI1,
GNPDA1,
SRA1,
TDRD15,
HMGN1P30,
PDCD6IP,
PDCD6,
MED16,
ADA,
CHAF1A,
TOM1,
RANBP9,
SMC4,
ARPC4-TTLL3,
RBM14-RBM4,
RNF103-CHMP3,
CHURC1-FNTB,
AP1M2,
ISY1-RAB43,
UBA2,
SAE1,
FARSB,
DNM1L,
ABCF2,
COX17,
SCAMP2,
SCAMP3,
DPP3,
SNUPN,
HUWE1,
TSSC4,
ATP9A,
PQBP1,
COL4A3BP,
PTGES3L-AARSD1,
ARPC5,
ARPC4,
ARPC3,
ARPC1B,
ACTR3,
ACTR2,
NUBP2,
PPIF,
LOC101060521,
ARPC2,
RAD50,
ACTR1B,
ACTR1A,
ADAM8,
LRPPRC,
PDIA6,
TRAP1,
BCAP31,
NAMPT,
RBM12,
G3BP1,
ABI2,
CEBPZ,
TRIM28,
AASS,
ATP6AP2,
WASF2,
SLC25A13,
CDK2,
RBM7,
ALYREF,
TXNDC9,
LOC101929876,
PSME3,
MPHOSPH10,
MPHOSPH6,
CDK5,
NUTF2,
EIF1,
DDX39A,
PSMD14,
CDK7,
PLIN3,
HNRNPR,
MRPS31,
CDK8,
RABEPK,
RIDA,
SRRM1,
CDK9,
STAM2,
SF3B4,
ZMPSTE24,
AKAP8,
STUB1,
STAG1,
UBE4B,
PRSS16,
SIGMAR1,
BET1,
CWC27,
SAP18
|
| 25814554 |
Phospho-tyrosine dependent protein-protein interaction network. Mol. Syst. Biol. Arndt Grossmann , Nouhad Benlasfer , Petra Birth , Anna Hegele , Franziska Wachsmuth , Luise Apelt , Ulrich Stelzl |
2015-03-01 |
SH2B3,
SH2D3A,
HUWE1,
FSBP,
TSPAN2,
TNK2,
SPRY2,
APBB3,
TRDN,
ANAPC10,
BAIAP2,
ZNHIT1,
SEMA4D,
UBD,
CENPB,
POLR3F,
RAI2,
SDCCAG8,
FRS3,
FRS2,
PGRMC1,
CYP46A1,
ARID5A,
NMU,
RALBP1,
YWHAQ,
LECT1,
CYB561D2,
RCAN3,
CAPN10,
FSTL1,
RASSF1,
CHN2,
TP53RK,
EFHC1,
OSBPL6,
C1QTNF3,
DDIT4L,
FAM46B,
CKM,
TM4SF19,
RBP7,
OLIG1,
CLNK,
SH2D1B,
TWIST2,
ASCL4,
SOCS4,
COX6B2,
GABPB2,
SHE,
VSTM2L,
C22orf39,
PPP1R21,
SCLT1,
PACRGL,
SETD9,
C6orf141,
MAGEC3,
DCAF12L1,
CRK,
CRKL,
CRP,
TCP10L,
ASB8,
ASB9,
CRYBA2,
CSK,
DUSP18,
FAM117B,
PLB1,
IQUB,
WBSCR27,
CYP2C8,
DBN1,
PAQR7,
DDX5,
LIX1,
GLIS3,
DOK1,
EPYC,
DTNA,
E2F2,
E2F6,
PHC2,
KRTCAP2,
ELK1,
ADCK5,
EPS8,
AKT1,
ESD,
MECOM,
EYA3,
EZH2,
FABP7,
FANCG,
MPEG1,
LNX2,
FAM217A
|
| 23455924 |
A Y2H-seq approach defines the human protein methyltransferase interactome. Nat. Methods Mareike Weimann , Arndt Grossmann , Jonathan Woodsmith , Ziya Ãzkan , Petra Birth , David Meierhofer , Nouhad Benlasfer , Taras Valovka , Bernd Timmermann , Erich E Wanker , Sascha Sauer , Ulrich Stelzl |
2013-04-01 |
HMGXB4,
NR1H3,
AKAP9,
PRMT3,
SPRY2,
PRMT5,
MCRS1,
ECI2,
BAIAP2,
TADA3,
SYNCRIP,
CARM1,
BATF,
SLU7,
POLR3F,
MYL12A,
STARD10,
UTP14A,
MALT1,
SPIN1,
SF3B2,
NUDT21,
ATE1,
RASSF1,
RASSF8,
PMF1,
SNF8,
PNKP,
CDCA5,
OIP5,
LENG8,
HAUS1,
NOSTRIN,
CCDC151,
DNTTIP1,
RAB3IP,
SSX2IP,
CLK1,
CLK3,
ZNF641,
IKBIP,
AEBP2,
FRMD6,
CDYL2,
KRT222,
ZNF57,
GABPB2,
UBXN10,
TSACC,
ZNF280A,
NUDCD2,
ASB10,
VPS37A,
FOXR2,
ZFP28,
FAM76B,
ZNF480,
CCDC155,
C20orf196,
LCA5L,
SMYD1,
SPICE1,
FGD5,
SAMD3,
WBSCR27,
C8orf48,
AK8,
ADSS,
DYX1C1,
DAXX,
SPRED1,
C18orf54,
FAM9A,
DXO,
PHC2,
SPATA24,
C8orf74,
ETV3,
MECOM,
EWSR1,
EZH2,
JMJD1C,
ZUFSP,
MTF2,
CEP162,
BAHD1,
WDFY3,
KDM1A,
KDM4B,
SEPT6,
DIP2A,
MLC1,
JMJD6,
ITGB3BP,
BRD4,
TTC33,
ZKSCAN5,
STAC3,
FUS
|
| 23800289 |
Orphanet J Rare Dis Teresa Esposito , Simone Sampaolo , Giuseppe Limongelli , Antonio Varone , Daniela Formicola , Daria Diodato , Olimpia Farina , Filomena Napolitano , Giuseppe Pacileo , Fernando Gianfrancesco , Giuseppe Di Iorio |
2013-01-01 |
ITGA7,
MYH7B
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员