| Type | Description |
|---|---|
| Definition | leucine rich repeat neuronal 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-11-30 10:16:00 | Authors found that LRRN1 contributes to pluripotency of hESC by preventing translocation of OCT4, NANOG, and SOX2 from nucleus to cytoplasm, thereby lessening their post-translational modification and degradation. | 29893054 |
| 2019-07-20 11:25:00 | Study found that LRRN1 is upregulated in gastric cancer (GC) tissue samples and its expression is closely related to poor prognosis. Knocking down LRRN1 expression promoted GC cell apoptosis, and activated the Fas/FasL pathway. | 31087525 |
| 2018-05-26 11:10:00 | NLRR1 appears to be an extracellular negative regulator of ALK signalling in neuroblastoma and neuronal development. | 27604320 |
| 2010-09-15 22:06:00 | Observational study of gene-disease association. (HuGE Navigator) | 20678249 |
| 2010-01-21 00:00:00 | N-MYC promotes cell proliferation through a direct transactivation of neuronal leucine-rich repeat protein-1 (NLRR1) gene in neuroblastoma. | 18591937 |
| Type | IDs |
|---|---|
| Synonymous | FIGLER3, NLRR-1 |
| Gene |
UniProtKB-ID:
LRRN1_HUMAN,
A8K6Q2_HUMAN
UniprotKB:
Q6UXK5,
A8K6Q2
UniParc:
UPI00015DA8C8,
UPI0000034CB8
EMBL:
AB040930,
AK023273,
BC034947,
AB074161,
AK291717,
AY358312
Ensembl:
ENSG00000175928
KO:
hsa:57633
|
| Nucleutide sequences |
EMBL-CDS:
BAA96021.1,
AAH34947.1,
AAQ88679.1,
BAB14500.1,
BAE45733.1,
BAF84406.1
Gene_ORFName:
Nbla10449,
UNQ693/PRO1338
Ensembl_TRS:
ENST00000319331
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000314901
RefSeq:
NP_065924.3,
NP_001311118.1,
NP_001311117.1
|
| Others |
UniRef100:
UniRef100_A8K6Q2,
UniRef100_Q6UXK5
UniRef90:
UniRef90_Q6UXK5
UniRef50:
UniRef50_Q6UXK5
UniGene:
Hs.163244
CCDS:
CCDS33685.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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