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57617 VPS18

57617

VPS18

VPS18 core subunit of CORVET and HOPS complexes

protein-coding

Homo sapiens

基因描述

Type Description
Definition VPS18 core subunit of CORVET and HOPS complexes

研究结论

Date Results Publications
2019-06-15 11:02:00 Study characterized the ubiquitinomes of Vps11/18 and demonstrated that these two factors are involved in the regulation of signal transduction by protein ubiquitination. VPS11/18 regulate several signaling factors and pathways, including Wnt, estrogen receptor alpha (ERalpha), and NFkappaB. 31015428
2017-10-28 11:24:00 VPS18 recruits VPS41 to the human HOPS complex via a RING-RING interaction 28931724
2011-07-16 11:30:00 Depletion of hVps18 or hMon2 reduced the efficient production of infectious HIV-1 virions in human cells. 21450827
2010-01-21 00:00:00 hVPS18 may play an important role in regulation of SNK activity through its ubiquitin ligase 16203730
2010-01-21 00:00:00 ubiquitin binding and ubiquitylation of GGA3-GAT domain are mutually inseparable through a ubiquitin ligase activity of hVPS18 16996030

名称对应

Type IDs
Synonymous PEP3
Gene
UniProtKB-ID: VPS18_HUMAN, A0A024R9R3_HUMAN
UniprotKB: Q9P253, A0A024R9R3
UniParc: UPI0000049FBC
EMBL: CH471125, BC001513, AB040908, AF308802, AL713725
Ensembl: ENSG00000104142
KO: hsa:57617
Nucleutide sequences
EMBL-CDS: AAG34679.1, BAA95999.1, CAD28515.1, AAH01513.1, EAW92464.1, EAW92465.1
Gene_ORFName: hCG_38959
Ensembl_TRS: ENST00000220509
Protein sequencees
Ensembl_PRO: ENSP00000220509
RefSeq: XP_011520146.1, XP_011520145.1, NP_065908.1, XP_016877936.1
Others
UniRef100: UniRef100_Q9P253
UniRef90: UniRef90_Q9P253
UniRef50: UniRef50_Q9P253
UniGene: Hs.23876
CCDS: CCDS10069.1

全选

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