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57602 USP36

57602

USP36

ubiquitin specific peptidase 36

protein-coding

Homo sapiens

基因描述

Type Description
Definition ubiquitin specific peptidase 36

研究结论

Date Results Publications
2021-01-16 16:00:00 The deubiquitinase USP36 Regulates DNA replication stress and confers therapeutic resistance through PrimPol stabilization. 33237263
2020-06-20 10:43:00 USP36 as regulator for the Parkin-dependent mitophagy at least in part via the Beclin-1-ATG14L pathway. 31550441
2020-05-02 11:35:00 USP36 overexpression decreased ischemia-induced apoptosis and oxidative stress in human renal tubular HK-2cells. The protein levels of c-Myc and SOD2 were declined in ischemic HK-2cells with enhanced ubiquitination. USP36 overexpression stabilized c-Myc and SOD2 by preventing ischemia-induced ubiquitination of both proteins. 30975468
2019-03-02 10:43:00 USP36 regulates PME-1 as a DUB and participates in the ERK and Akt signaling pathways 29577269
2018-02-17 11:19:00 Together, our results reveal USP36 as a novel H2B deubiquitinase and shed light on its additional functions in regulating gene expression. 29274341

名称对应

Type IDs
Synonymous DUB1
Gene
UniProtKB-ID: UBP36_HUMAN, A0A024R8V6_HUMAN
UniprotKB: Q9P275, A0A024R8V6
UniParc: UPI00000398BB
EMBL: BC071582, BC016487, AL833835, AB040886, AK001671, CH471099, BC027992
Ensembl: ENSG00000055483
KO: hsa:57602
Nucleutide sequences
EMBL-CDS: CAD38695.1, AAH71582.1, BAA91825.1, AAH27992.1, AAH16487.1, BAA95977.1, EAW89534.1, EAW89536.1, EAW89535.1
Gene_ORFName: hCG_95566
Ensembl_TRS: ENST00000542802, ENST00000312010, ENST00000589225
Protein sequencees
Ensembl_PRO: ENSP00000467280, ENSP00000441214, ENSP00000310590
RefSeq: XP_016880390.1, NP_001372104.1, XP_011523367.1, NP_001372109.1, NP_001372101.1, NP_001372107.1, XP_024306614.1, NP_001372102.1, XP_011523370.1, XP_011523368.1, NP_001308220.1, NP_001372098.1, NP_001372103.1, NP_001372100.1, XP_011523371.1, NP_001372106.1, XP_024306613.1, NP_001372108.1, XP_011523372.1, NP_001372099.1, XP_011523373.1, NP_001372105.1
Others
UniRef100: UniRef100_Q9P275
UniRef90: UniRef90_Q9P275
UniRef50: UniRef50_Q9P275
UniGene: Hs.464243
CCDS: CCDS32755.1

全选

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