| Type | Description |
|---|---|
| Definition | WD repeat domain 48 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-02 12:51:00 | The DNA-binding activity of USP1-associated factor 1 is required for efficient RAD51-mediated homologous DNA pairing and homology-directed DNA repair. | 32350107 |
| 2019-05-25 12:09:00 | In this report, the authors provide evidence that the previously described interaction between the viral E1 helicase and the cellular UAF1-USP1 deubiquitinating enzyme complex is required for the completion of the bidirectional theta replication of the human papilloma virus type 11 genome and the subsequent initiation of the unidirectional replication. | 30890612 |
| 2018-04-14 11:42:00 | There is evidence that USP1/WDR48 complex promotes cancer stem cell conservation and regulation of DNA damage repair. [REVIEW] | 28302046 |
| 2017-12-23 12:38:00 | Our results highlight the interfaces essential for regulation of USP12 activity and show a conserved second binding of UAF1 which could be important for regulatory functions independent of USP12 activity. | 27650958 |
| 2017-12-23 11:48:00 | These results outline a novel mechanism for the control of TBK1 activity and suggest USP1-UAF1 complex as a potential target for the prevention of viral diseases. | 29138248 |
| Type | IDs |
|---|---|
| Synonymous | P80, SPG60, UAF1 |
| Gene |
UniProtKB-ID:
WDR48_HUMAN,
A0A024R2L1_HUMAN
UniprotKB:
Q8TAF3,
A0A024R2L1
UniParc:
UPI000006FF8C,
UPI00017A7729,
UPI00006275E6,
UPI00017A75B2,
UPI00005A4204
EMBL:
AK302307,
BC026353,
AB040882,
AF468833,
BX649170,
AK298810,
BC037168,
HM005537,
AK297349,
AL162064,
AL832926,
CH471055
Ensembl:
ENSG00000114742
KO:
hsa:57599
|
| Nucleutide sequences |
EMBL-CDS:
BAG60944.1,
CAB82402.1,
BAA95973.2,
BAG63646.1,
BAG59798.1,
AAH26353.1,
AAH37168.1,
AAL78650.1,
CAH56300.1,
CAH56182.1,
EAW64550.1,
EAW64551.1,
AEE61134.1
Gene_ORFName:
hCG_19029
Ensembl_TRS:
ENST00000302313
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000307491
RefSeq:
NP_001290332.1,
XP_011532273.1,
XP_005265403.1,
NP_001333156.1,
NP_001333154.1,
NP_001290331.1,
NP_065890.1,
NP_001333157.1,
NP_001333155.1
|
| Others |
UniRef100:
UniRef100_Q8TAF3
UniRef90:
UniRef90_Q8TAF3
UniRef50:
UniRef50_Q8TAF3
UniGene:
Hs.109778
CCDS:
CCDS33738.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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