| Type | Description |
|---|---|
| Definition | dedicator of cytokinesis 6 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-02 12:48:00 | Expanding the phenotype in Adams-Oliver syndrome correlating with the genotype. | 31654484 |
| 2020-04-11 10:30:00 | DOCK6 localizes to the endoplasmic reticulum (ER) in dependence of its DHR-1 domain. | 28287327 |
| 2019-05-18 12:37:00 | Results identified c.4106rC and c.3063 C>G mutations in the DOCK6 gene in a 5-year-old Chinese girl with the phenotype of Adams-Oliver syndrome (AOS). When caused by mutations in the DOCK6 gene, the AOS inheritance pattern is autosomal recessive. The two mutations carried by the patient were inherited from the father and mother respectively, generating compound heterozygosity in the patient. | 30898718 |
| 2019-05-11 10:58:00 | Dock6 was over-expressed in GC tissues, and its positive expression was associated with GC metastasis and indicated poor prognosis of GC patients. | 29587866 |
| 2017-06-24 11:59:00 | acute knockdown of the Adams-Oliver syndrome (AOS) gene DOCK6, coding for a RAC1/CDC42 guanine nucleotide exchange factor, results in strikingly different phenotypes to those generated by genomic DOCK6 disruption. | 27693507 |
| Type | IDs |
|---|---|
| Synonymous | AOS2, ZIR1 |
| Gene |
UniProtKB-ID:
DOCK6_HUMAN,
B7Z9U8_HUMAN
UniprotKB:
Q96HP0,
B7Z9U8
UniParc:
UPI0001915382,
UPI000059D66F
EMBL:
AC011472,
AC009000,
AK316063,
AB037816,
BC008335,
BC051330,
BC146786
Ensembl:
ENSG00000130158
KO:
hsa:57572
|
| Nucleutide sequences |
EMBL-CDS:
BAA92633.2,
AAI46787.1,
AAH51330.1,
AAH08335.2,
BAH14434.1
Ensembl_TRS:
ENST00000294618
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000294618
RefSeq:
XP_011526454.1,
XP_011526452.1,
NP_065863.2,
XP_011526453.1,
NP_001354759.1,
XP_005260057.1,
XP_006722867.1
|
| Others |
UniRef100:
UniRef100_Q96HP0,
UniRef100_B7Z9U8
UniRef90:
UniRef90_K7ESB7,
UniRef90_Q96HP0
UniRef50:
UniRef50_Q96HP0,
UniRef50_K7ESB7
UniGene:
Hs.591002
CCDS:
CCDS45975.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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