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5757 PTMA

5757

PTMA

prothymosin alpha

protein-coding

Homo sapiens

基因描述

Type Description
Definition prothymosin alpha

研究结论

Date Results Publications
2021-03-28 19:06:00 Prothymosin alpha activates type I collagen to develop a fibrotic placenta in gestational diabetes. 32909608
2020-01-18 10:59:00 Dynamics of the intrinsically disordered protein NUPR1 in isolation and in its fuzzy complexes with DNA and prothymosin alpha. 31325636
2019-08-03 10:46:00 Measure the binding affinity for the prothymosin-alpha (ProTalpha)-H1.0 complex using isothermal titration calorimetry and report a KD value of (4.6 +/- 0.5) x 10(-7) M. In addition, we show that ProTalpha facilitates the formation of the H1.0-nucleosome complex in vitro. 30430826
2019-04-20 12:22:00 Our data support that nuclear PTMA protein serves as a tumor suppressor in bladder cancer through upregulating PTEN and orchestrating TRIM21 for the regulation of Nrf2 signaling. 30719818
2017-12-02 11:01:00 According to the cellular function of the characterized targets of ProTalpha, and the evolution in the composition of the diverse ProTalpha-complexes when proliferation activity was reduced or apoptosis induced, leads to hypothesized that ProTalpha interactions might be related to the proliferation activity and control of the cell survival. 29106904

名称对应

Type IDs
Synonymous TMSA
Gene
UniProtKB-ID: PTMA_HUMAN, Q53S24_HUMAN
UniprotKB: P06454, Q53S24
UniParc: UPI0000000B0B, UPI0000047512
EMBL: S56449, J04797, BC071879, BC071647, M26708, AF348514, BC034921, BC098420, AK314106, BC003510, AC073476, M14630, BC070480, BC051265, AK223605, BC066905, M67480, M14483
Ensembl: ENSG00000187514
KO: hsa:5757
Nucleutide sequences
EMBL-CDS: AAH51265.1, AAA63239.1, AAH71879.1, AAA60213.1, AAA61182.1, AAA63240.1, AAH70480.1, AAA61183.1, AAH71647.1, AAD13882.1, AAK30146.1, AAH66905.1, AAH98420.1, BAD97325.1, AAH03510.1, AAY24150.1, BAG36799.1, AAH34921.1
Ensembl_TRS: ENST00000409115, ENST00000341369
Protein sequencees
Ensembl_PRO: ENSP00000386819, ENSP00000344547
RefSeq: NP_002814.3, NP_001092755.1
Others
UniRef100: UniRef100_P06454, UniRef100_Q53S24
UniRef90: UniRef90_Q53S24, UniRef90_P06454
UniRef50: UniRef50_P06454
UniGene: Hs.459927
CCDS: CCDS42833.1, CCDS46541.1

全选

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