| Type | Description |
|---|---|
| Definition | kelch like family member 8 |
| Date | Results | Publications |
|---|---|---|
| 2010-12-05 22:08:00 | Observational study of gene-disease association. (HuGE Navigator) | 20800603 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
KLHL8_HUMAN,
Q7Z330_HUMAN,
B3KY78_HUMAN,
Q68DU9_HUMAN
UniprotKB:
Q9P2G9,
Q7Z330,
B3KY78,
Q68DU9
UniParc:
UPI00004A292B,
UPI00001AE9B8,
UPI00001A9DC0,
UPI000022C3A0,
UPI00001BDBAD
EMBL:
AB037799,
BX640744,
AK128827,
BX538173,
CR749265,
BX640727,
CH471057,
BC041384,
AC092658,
AC108516
Ensembl:
ENSG00000145332
KO:
hsa:57563
|
| Nucleutide sequences |
EMBL-CDS:
CAE45855.1,
CAE45843.1,
BAA92616.2,
EAX05982.1,
AAH41384.1,
CAD98048.1,
BAG54740.1,
CAH18121.1
Ensembl_TRS:
ENST00000273963,
ENST00000498875,
ENST00000512111,
ENST00000425278
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000273963,
ENSP00000426451,
ENSP00000424131,
ENSP00000408854
RefSeq:
NP_001278935.1,
NP_001278932.1,
NP_065854.3,
NP_001278936.1
|
| Others |
UniRef100:
UniRef100_Q7Z330,
UniRef100_Q68DU9,
UniRef100_Q9P2G9,
UniRef100_B3KY78
UniRef90:
UniRef90_Q68DU9,
UniRef90_Q9P2G9
UniRef50:
UniRef50_Q9P2G9,
UniRef50_Q68DU9
UniGene:
Hs.106601
CCDS:
CCDS77937.1,
CCDS3617.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 32296183 |
A reference map of the human binary protein interactome. Nature Katja Luck , Dae-Kyum Kim , Luke Lambourne , Kerstin Spirohn , Bridget E Begg , Wenting Bian , Ruth Brignall , Tiziana Cafarelli , Francisco J Campos-Laborie , Benoit Charloteaux , Dongsic Choi , Atina G Coté , Meaghan Daley , Steven Deimling , Alice Desbuleux , Amélie Dricot , Marinella Gebbia , Madeleine F Hardy , Nishka Kishore , Jennifer J Knapp , István A Kovács , Irma Lemmens , Miles W Mee , Joseph C Mellor , Carl Pollis , Carles Pons , Aaron D Richardson , Sadie Schlabach , Bridget Teeking , Anupama Yadav , Mariana Babor , Dawit Balcha , Omer Basha , Christian Bowman-Colin , Suet-Feung Chin , Soon Gang Choi , Claudia Colabella , Georges Coppin , Cassandra D'Amata , David De Ridder , Steffi De Rouck , Miquel Duran-Frigola , Hanane Ennajdaoui , Florian Goebels , Liana Goehring , Anjali Gopal , Ghazal Haddad , Elodie Hatchi , Mohamed Helmy , Yves Jacob , Yoseph Kassa , Serena Landini , Roujia Li , Natascha van Lieshout , Andrew MacWilliams , Dylan Markey , Joseph N Paulson , Sudharshan Rangarajan , John Rasla , Ashyad Rayhan , Thomas Rolland , Adriana San-Miguel , Yun Shen , Dayag Sheykhkarimli , Gloria M Sheynkman , Eyal Simonovsky , Murat TaÅan , Alexander Tejeda , Vincent Tropepe , Jean-Claude Twizere , Yang Wang , Robert J Weatheritt , Jochen Weile , Yu Xia , Xinping Yang , Esti Yeger-Lotem , Quan Zhong , Patrick Aloy , Gary D Bader , Javier De Las Rivas , Suzanne Gaudet , Tong Hao , Janusz Rak , Jan Tavernier , David E Hill , Marc Vidal , Frederick P Roth , Michael A Calderwood |
2020-04-01 | - |
| 30344098 |
Ubiquitin-Independent Disassembly by a p97 AAA-ATPase Complex Drives PP1 Holoenzyme Formation. Mol. Cell Matthias Weith , Jonas Seiler , Johannes van den Boom , Matthias Kracht , Julia Hülsmann , Ivana Primorac , Javier Del Pino Garcia , Farnusch Kaschani , Markus Kaiser , Andrea Musacchio , Mathieu Bollen , Hemmo Meyer |
2018-11-15 | - |
| 29987050 |
Proc. Natl. Acad. Sci. U.S.A. Tengfei Xiao , Wei Li , Xiaoqing Wang , Han Xu , Jixin Yang , Qiu Wu , Ying Huang , Joseph Geradts , Peng Jiang , Teng Fei , David Chi , Chongzhi Zang , Qi Liao , Jonathan Rennhack , Eran Andrechek , Nanlin Li , Simone Detre , Mitchell Dowsett , Rinath M Jeselsohn , X Shirley Liu , Myles Brown |
2018-07-31 | - |
| 28514442 |
Architecture of the human interactome defines protein communities and disease networks. Nature Edward L Huttlin , Raphael J Bruckner , Joao A Paulo , Joe R Cannon , Lily Ting , Kurt Baltier , Greg Colby , Fana Gebreab , Melanie P Gygi , Hannah Parzen , John Szpyt , Stanley Tam , Gabriela Zarraga , Laura Pontano-Vaites , Sharan Swarup , Anne E White , Devin K Schweppe , Ramin Rad , Brian K Erickson , Robert A Obar , K G Guruharsha , Kejie Li , Spyros Artavanis-Tsakonas , Steven P Gygi , J Wade Harper |
2017-05-25 | - |
| 26496610 |
A human interactome in three quantitative dimensions organized by stoichiometries and abundances. Cell Marco Y Hein , Nina C Hubner , Ina Poser , Jürgen Cox , Nagarjuna Nagaraj , Yusuke Toyoda , Igor A Gak , Ina Weisswange , Jörg Mansfeld , Frank Buchholz , Anthony A Hyman , Matthias Mann |
2015-10-22 |
Cep85l,
Rcc1,
Zbtb48,
Bsdc1,
Kifc1,
Ccp110,
Ints4,
Slc6a8,
Cenpi,
Nup107,
Xpo1,
Fbxw11,
Tubg1,
Csnk1d,
Bap1,
Ptpn23,
Tecpr2,
Slain1,
Ankrd28,
Prkaa1,
Espl1,
Gbf1,
Cdc20,
Cenpf,
Trip11,
Mbd5,
Kif22,
Dut,
Srsf1,
Actb,
Spred2,
Akt2,
Mta1,
Tgs1,
Pip4k2c,
Ankfy1,
Apc,
Ar,
Rhoa,
Atp2a2,
Atp5a1,
Atp7a,
Cep131,
Bach1,
Bcl7c,
Bmpr1a,
Brca1,
Bub1,
Bub1b,
C1qbp,
Anxa2,
Calu,
Cbx1,
Cbx4,
Cct2,
Cct3,
Cct4,
Cct7,
Cct8,
Cd2ap,
Cdk1,
Cdc37,
Cdh1,
Chek1,
Cit,
Copa,
Crebbp,
Cry1,
Csk,
Smc3,
Dctn1,
Ddb1,
Cdk2ap1,
Mapre1,
Ect2,
Eef1a1,
Eif3a,
Mark2,
Evpl,
Ewsr1,
Wdr5,
Dclre1b,
Fbl,
Fgfr1,
Flot1,
Flot2,
B4galt1,
Gnb1,
Gspt1,
Hdac6,
Herc2,
Hsf1,
Hsph1,
Elavl1,
Id2,
Cyr61,
Cep250,
Insr,
Eif3e
|
| 24457600 |
The central role of EED in the orchestration of polycomb group complexes. Nat Commun Qi Cao , Xiaoju Wang , Meng Zhao , Rendong Yang , Rohit Malik , Yuanyuan Qiao , Anton Poliakov , Anastasia K Yocum , Yong Li , Wei Chen , Xuhong Cao , Xia Jiang , Arun Dahiya , Clair Harris , Felix Y Feng , Sundeep Kalantry , Zhaohui S Qin , Saravana M Dhanasekaran , Arul M Chinnaiyan |
2014-01-01 | - |
| 24097068 |
Discovery and refinement of loci associated with lipid levels. Nat. Genet. Cristen J Willer , Ellen M Schmidt , Sebanti Sengupta , Gina M Peloso , Stefan Gustafsson , Stavroula Kanoni , Andrea Ganna , Jin Chen , Martin L Buchkovich , Samia Mora , Jacques S Beckmann , Jennifer L Bragg-Gresham , Hsing-Yi Chang , AyÅe Demirkan , Heleen M Den Hertog , Ron Do , Louise A Donnelly , Georg B Ehret , Tõnu Esko , Mary F Feitosa , Teresa Ferreira , Krista Fischer , Pierre Fontanillas , Ross M Fraser , Daniel F Freitag , Deepti Gurdasani , Kauko Heikkilä , Elina Hyppönen , Aaron Isaacs , Anne U Jackson , à sa Johansson , Toby Johnson , Marika Kaakinen , Johannes Kettunen , Marcus E Kleber , Xiaohui Li , Jian'an Luan , Leo-Pekka Lyytikäinen , Patrik K E Magnusson , Massimo Mangino , Evelin Mihailov , May E Montasser , Martina Müller-Nurasyid , Ilja M Nolte , Jeffrey R O'Connell , Cameron D Palmer , Markus Perola , Ann-Kristin Petersen , Serena Sanna , Richa Saxena , Susan K Service , Sonia Shah , Dmitry Shungin , Carlo Sidore , Ci Song , Rona J Strawbridge , Ida Surakka , Toshiko Tanaka , Tanya M Teslovich , Gudmar Thorleifsson , Evita G Van den Herik , Benjamin F Voight , Kelly A Volcik , Lindsay L Waite , Andrew Wong , Ying Wu , Weihua Zhang , Devin Absher , Gershim Asiki , Inês Barroso , Latonya F Been , Jennifer L Bolton , Lori L Bonnycastle , Paolo Brambilla , Mary S Burnett , Giancarlo Cesana , Maria Dimitriou , Alex S F Doney , Angela Döring , Paul Elliott , Stephen E Epstein , Gudmundur Ingi Eyjolfsson , Bruna Gigante , Mark O Goodarzi , Harald Grallert , Martha L Gravito , Christopher J Groves , Göran Hallmans , Anna-Liisa Hartikainen , Caroline Hayward , Dena Hernandez , Andrew A Hicks , Hilma Holm , Yi-Jen Hung , Thomas Illig , Michelle R Jones , Pontiano Kaleebu , John J P Kastelein , Kay-Tee Khaw , Eric Kim , Norman Klopp , Pirjo Komulainen , Meena Kumari , Claudia Langenberg , Terho Lehtimäki , Shih-Yi Lin , Jaana Lindström , Ruth J F Loos , François Mach , Wendy L McArdle , Christa Meisinger , Braxton D Mitchell , Gabrielle Müller , Ramaiah Nagaraja , Narisu Narisu , Tuomo V M Nieminen , Rebecca N Nsubuga , Isleifur Olafsson , Ken K Ong , Aarno Palotie , Theodore Papamarkou , Cristina Pomilla , Anneli Pouta , Daniel J Rader , Muredach P Reilly , Paul M Ridker , Fernando Rivadeneira , Igor Rudan , Aimo Ruokonen , Nilesh Samani , Hubert Scharnagl , Janet Seeley , Kaisa Silander , Alena StanÄáková , Kathleen Stirrups , Amy J Swift , Laurence Tiret , Andre G Uitterlinden , L Joost van Pelt , Sailaja Vedantam , Nicholas Wainwright , Cisca Wijmenga , Sarah H Wild , Gonneke Willemsen , Tom Wilsgaard , James F Wilson , Elizabeth H Young , Jing Hua Zhao , Linda S Adair , Dominique Arveiler , Themistocles L Assimes , Stefania Bandinelli , Franklyn Bennett , Murielle Bochud , Bernhard O Boehm , Dorret I Boomsma , Ingrid B Borecki , Stefan R Bornstein , Pascal Bovet , Michel Burnier , Harry Campbell , Aravinda Chakravarti , John C Chambers , Yii-Der Ida Chen , Francis S Collins , Richard S Cooper , John Danesh , George Dedoussis , Ulf de Faire , Alan B Feranil , Jean Ferrières , Luigi Ferrucci , Nelson B Freimer , Christian Gieger , Leif C Groop , Vilmundur Gudnason , Ulf Gyllensten , Anders Hamsten , Tamara B Harris , Aroon Hingorani , Joel N Hirschhorn , Albert Hofman , G Kees Hovingh , Chao Agnes Hsiung , Steve E Humphries , Steven C Hunt , Kristian Hveem , Carlos Iribarren , Marjo-Riitta Järvelin , Antti Jula , Mika Kähönen , Jaakko Kaprio , Antero Kesäniemi , Mika Kivimaki , Jaspal S Kooner , Peter J Koudstaal , Ronald M Krauss , Diana Kuh , Johanna Kuusisto , Kirsten O Kyvik , Markku Laakso , Timo A Lakka , Lars Lind , Cecilia M Lindgren , Nicholas G Martin , Winfried März , Mark I McCarthy , Colin A McKenzie , Pierre Meneton , Andres Metspalu , Leena Moilanen , Andrew D Morris , Patricia B Munroe , Inger Njølstad , Nancy L Pedersen , Chris Power , Peter P Pramstaller , Jackie F Price , Bruce M Psaty , Thomas Quertermous , Rainer Rauramaa , Danish Saleheen , Veikko Salomaa , Dharambir K Sanghera , Jouko Saramies , Peter E H Schwarz , Wayne H-H Sheu , Alan R Shuldiner , Agneta Siegbahn , Tim D Spector , Kari Stefansson , David P Strachan , Bamidele O Tayo , Elena Tremoli , Jaakko Tuomilehto , Matti Uusitupa , Cornelia M van Duijn , Peter Vollenweider , Lars Wallentin , Nicholas J Wareham , John B Whitfield , Bruce H R Wolffenbuttel , Jose M Ordovas , Eric Boerwinkle , Colin N A Palmer , Unnur Thorsteinsdottir , Daniel I Chasman , Jerome I Rotter , Paul W Franks , Samuli Ripatti , L Adrienne Cupples , Manjinder S Sandhu , Stephen S Rich , Michael Boehnke , Panos Deloukas , Sekar Kathiresan , Karen L Mohlke , Erik Ingelsson , Gonçalo R Abecasis , Global Lipids Genetics Consortium |
2013-11-01 | - |
| 23568457 |
Genetic variants associated with disordered eating. Int J Eat Disord Tracey D Wade , Scott Gordon , Sarah Medland , Cynthia M Bulik , Andrew C Heath , Grant W Montgomery , Nicholas G Martin |
2013-09-01 |
SH2D3C,
C8orf37-AS1,
TSHZ1,
OLIG2,
ZER1,
PHTF1,
OR9A4,
SGPP2,
ADH7,
C4orf36,
CHODL,
MACROD2,
TEKT5,
DAB1,
CNBD1,
DNASE1L3,
EMP2,
ATOH7,
FLG,
FLNB,
CLEC5A,
MAGI3,
CCDC69,
GM2A,
LOC284395,
NKAIN3,
GRID1,
PKN3,
FLG-AS1,
GADL1,
VSTM2B,
HSD17B13,
CATSPER3,
FLG2,
AFF1,
MSRA,
NCL,
WEE2,
CRNN,
TAS2R3,
TAS2R4,
HSD17B11,
PDE6D,
PDE8A,
WWOX,
ATP8A2,
PITX1,
TAS2R5,
CDV3,
PRM1,
PRM2,
TMPRSS15,
CAMK1D,
TAS2R38,
KLHL8,
PTMA,
QSOX1,
PRM3,
RASGRF2,
ROBO2,
CCL20,
PERP,
SET,
CSMD1,
SMTN,
SSBP1,
TNP2,
MCTP1,
SPHKAP,
TAS1R2,
C10orf11,
C4orf17,
PCBD2,
ZDHHC12,
KCNK5,
SOCS1,
ALDH4A1,
MGAM,
WDR34,
COL23A1,
NT5C1B,
SYTL5,
CEP350
|
| 23676014 |
Update on the Kelch-like (KLHL) gene family. Hum Genomics Bajinder S Dhanoa , Tiziana Cogliati , Akhila G Satish , Elspeth A Bruford , James S Friedman |
2013-05-15 | - |
| 20800603 |
Mutat. Res. Friederike Flachsbart , Andre Franke , Rabea Kleindorp , Amke Caliebe , Hélène Blanché , Stefan Schreiber , Almut Nebel |
2010-12-10 |
PDCD6IP,
INSL5,
CHAF1A,
HMGXB4,
SMC4,
PRG4,
COQ7,
SLC35B1,
TLR6,
GLRX3,
IQGAP2,
NEU3,
ME3,
MRPS30,
SPINK5,
DIDO1,
CHI3L1,
NUDT6,
CHIT1,
RASSF1,
BIRC8,
IL17F,
HELQ,
NLRP3,
RNF157,
SLC5A11,
GALNT15,
GSTO2,
CMA1,
GABPB2,
ADH4,
IQGAP3,
OSR1,
ADH7,
GLYCTK,
UGT3A1,
PXDNL,
CRYGB,
BNIPL,
CTSG,
KLB,
PRUNE2,
DCC,
HFM1,
CLYBL,
DLAT,
DNASE1,
DNASE1L3,
AGL,
TRDMT1,
DUSP6,
EGF,
NLRP7,
SLC5A9,
EMP1,
ENO3,
ERBB3,
ESR1,
FANCA,
FANCE,
PTK2B,
A2M,
FGL1,
HSPA4L,
NLRP1,
CARD8,
ATF6,
ACIN1,
FOXM1,
SETX,
SWAP70,
FLG,
FLT3,
MAN2B2,
KHNYN,
ARHGEF12,
SIRT5,
SIRT3,
ORC3,
PPP1R15A,
POLA2,
FRK,
FUCA1,
FUCA2,
FUT2,
GCA,
GALC,
ASF1A,
GALT,
GANC,
GAPDH,
LRIT1,
FBXO5,
GALNT8,
GBGT1,
GBE1,
GCKR,
GFRA2,
GIP
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
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目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
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目前还没有研究热点人员