| Type | Description |
|---|---|
| Definition | arrestin domain containing 3 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-02 13:22:00 | Upregulated ARRDC3 limits trophoblast cell invasion and tube formation and is associated with preeclampsia. | 31665660 |
| 2020-02-15 11:52:00 | Authors identified miR-200b as a major target gene of ARRDC3. miR-200b played an essential role in mediating ARRDC3 dependent reversal of EMT phenotypes and chemo-resistance to DNA damaging agents in TNBC cells. Expression of miR-200b also increased the expression of ARRDC3 as well in TNBC cells, suggesting a positive feedback loop between these two molecules. | 31295851 |
| 2020-02-15 10:51:00 | Study observed that the depletion of ARRDC3 in human hepatocytes resulted in the downregulation of inflammasome pathway-associated genes and the enhancement of apoptosis of hepatic stellate cells treated with their conditioned media. Results demonstrated ARRDC3 may play a role in the development of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis. | 31341404 |
| 2019-06-08 11:52:00 | ARRDC3 is involved in the infectious entry of human papillomavirus into the cell | 30412241 |
| 2019-01-12 12:04:00 | a critical link between the tumor suppressor ARRDC3 and regulation of GPCR trafficking and signaling in breast cancer | 29348172 |
| Type | IDs |
|---|---|
| Synonymous | TLIMP |
| Gene |
UniProtKB-ID:
ARRD3_HUMAN
UniprotKB:
Q96B67
UniParc:
UPI000006F2E2
EMBL:
BC015928,
AB037797,
AK291753,
BC053619
Ensembl:
ENSG00000113369
KO:
hsa:57561
|
| Nucleutide sequences |
EMBL-CDS:
BAA92614.1,
AAH53619.1,
BAF84442.1,
AAH15928.1
Ensembl_TRS:
ENST00000265138
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000265138
RefSeq:
NP_001316599.1,
NP_065852.1,
NP_001316601.1,
NP_001316600.1
|
| Others |
UniRef100:
UniRef100_Q96B67
UniRef90:
UniRef90_Q96B67
UniRef50:
UniRef50_Q96B67
UniGene:
Hs.24684
CCDS:
CCDS34202.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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