| Type | Description |
|---|---|
| Definition | neutral cholesterol ester hydrolase 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-11-28 13:18:00 | Retinoic acid receptor-related orphan receptor alpha reduces lipid droplets by upregulating neutral cholesterol ester hydrolase 1 in macrophages. | 32321446 |
| 2018-01-27 11:46:00 | Authors discovered that the presence of cholesterol, LDLR-mediated cholesterol endocytosis, and cholesterol efflux are all essential to NCEH-1-mediated neuroprotection. In protecting from alpha-synuclein neurotoxicity, NCEH-1 also stimulates cholesterol-derived neurosteroid formation and lowers cellular reactive oxygen species in mitochondria. | 28934392 |
| 2016-07-16 11:06:00 | Psoriasis inflammation induced microRNA targets NCEH1 in underlying subcutaneous adipose tissue. | 27015452 |
| 2016-06-04 10:48:00 | Together, the results define the kinetics of inhibition of KIAA1363 by active metabolites of agrochemicals and indicate that KIAA1363 is highly sensitive to inhibition by these compounds. | 26617293 |
| 2015-08-22 11:00:00 | Pioglitazone increases ABCA1 expression in an LXR-dependent manner and NCEH1 expression in an LXRalpha-independent manner. | 25280398 |
| Type | IDs |
|---|---|
| Synonymous | AADACL1, NCEH |
| Gene |
UniProtKB-ID:
NCEH1_HUMAN,
A0A0A0MTJ9_HUMAN
UniprotKB:
Q6PIU2,
A0A0A0MTJ9
UniParc:
UPI0000579781,
UPI000020A7D9,
UPI0001914B32,
UPI000199A4B7
EMBL:
AB037784,
AK294811,
AK299422,
AK316431,
AC007919,
AC069237,
AK295641,
BC028734,
BC047588,
AK304253
Ensembl:
ENSG00000144959
KO:
hsa:57552
|
| Nucleutide sequences |
EMBL-CDS:
BAH14802.1,
BAH14142.1,
BAA92601.1,
BAH11890.1,
AAH47588.2,
BAH12137.1,
BAH13028.1,
AAH28734.2
Ensembl_TRS:
ENST00000475381,
ENST00000543711,
ENST00000538775
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000418571,
ENSP00000443227,
ENSP00000442464
RefSeq:
NP_001139748.2,
NP_001139750.1,
NP_065843.4,
NP_001139749.1
|
| Others |
UniRef100:
UniRef100_Q6PIU2,
UniRef100_A0A0A0MTJ9
UniRef90:
UniRef90_Q6PIU2
UniRef50:
UniRef50_Q6PIU2
UniGene:
Hs.444099
CCDS:
CCDS54682.1,
CCDS54681.1,
CCDS33893.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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