| Type | Description |
|---|---|
| Definition | TAO kinase 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-03-14 11:33:00 | Variants in TAOK1 Cause Neurodevelopmental Disorders. | 31230721 |
| 2019-10-26 11:44:00 | These results demonstrate that TAOK1 is a negative regulator of IL-17 signaling and that it may have therapeutic utility as a target for the treatment of IL-17-associated inflammatory disorders. | 29400705 |
| 2018-07-28 10:03:00 | we characterize a compound that inhibits TAOK1 and TAOK2 activity with IC50 values of 11 to 15 nmol/L, is ATP-competitive, and targets these kinases selectively. TAOK inhibition or depletion in centrosome-amplified SKBR3 or BT549 breast cancer cell models increases the mitotic population, the percentages of mitotic cells displaying amplified centrosomes and multipolar spindles, induces cell death, and inhibits cell growt | 28830982 |
| 2018-07-07 10:46:00 | this study reveals a protective role for miR-706 by blocking the oxidative stress-induced activation of Our results further identify a major implication for miR-706 in preventing hepatic fibrogenesis and suggest that miR-706 may be a suitable molecular target for anti-fibrosis therapy. | 27876854 |
| 2017-10-07 13:02:00 | This study reports a novel set of Dengue virus (DENV) NS1-interacting host cell proteins in the HepG2 cell line and proposes possible roles for human NEK2, TAO1, and COG1 in DENV infection. | 27108190 |
| Type | IDs |
|---|---|
| Synonymous | KFC-B, MAP3K16, MARKK, PSK-2, PSK2, TAO1, hKFC-B, hTAOK1 |
| Gene |
UniProtKB-ID:
TAOK1_HUMAN,
A0A024QZ70_HUMAN
UniprotKB:
Q7L7X3,
A0A024QZ70
UniParc:
UPI000189A877,
UPI000004A033,
UPI00005C8A3D
EMBL:
BC133039,
CH471159,
AK024376,
AY049015,
CQ834802,
AC068588,
AF263312,
AC068025,
AB037782,
BC144067,
AC090698
Ensembl:
ENSG00000160551
KO:
hsa:57551
|
| Nucleutide sequences |
EMBL-CDS:
AAI33040.1,
EAW51188.1,
AAG38502.1,
CAH05616.1,
AAI44068.1,
AAL12217.1,
BAB14901.1,
BAA92599.1,
EAW51189.1,
EAW51190.1
Gene_ORFName:
hCG_1992959
Ensembl_TRS:
ENST00000536202,
ENST00000261716
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000261716,
ENSP00000438819
RefSeq:
NP_065842.1,
NP_079418.1
|
| Others |
UniRef100:
UniRef100_Q7L7X3
UniRef90:
UniRef90_Q7L7X3
UniRef50:
UniRef50_Q7L7X3
UniGene:
Hs.597434,
Hs.735869
CCDS:
CCDS32601.1,
CCDS56024.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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