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57521 RPTOR

57521

RPTOR

regulatory associated protein of MTOR complex 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition regulatory associated protein of MTOR complex 1

研究结论

Date Results Publications
2020-11-21 13:30:00 Knocking down raptor in human keratinocytes affects ornithine decarboxylase in a post-transcriptional Manner following ultraviolet B exposure. 30972602
2020-10-24 14:12:00 Upregulation of Akt/Raptor signaling is associated with rapamycin resistance of breast cancer cells. 32861747
2020-09-12 16:02:00 Expression of Raptor and Rictor and their relationships with angiogenesis in colorectal cancer. 32039630
2020-05-02 10:58:00 ryo-electron microscopy structure of RagA/RagC in complex with mTORC1 shows the details of RagA/RagC binding to the RAPTOR subunit of mTORC1 and explains why only the RagAGTP/RagCGDP nucleotide state binds mTORC1 31601764
2020-04-25 11:51:00 The Raptor alpha-solenoid directly detects the nucleotide state of RagA while the Raptor "claw" threads between the GTPase domains to detect that of RagC. Mutations that disrupted Rag-Raptor binding inhibited mTORC1 lysosomal localization and signaling. 31601708

名称对应

Type IDs
Synonymous KOG1, Mip1
Gene
UniProtKB-ID: RPTOR_HUMAN, Q6DKI0_HUMAN
UniprotKB: Q8N122, Q6DKI0
UniParc: UPI0001AE8261, UPI0000231C31, UPI00003BE967, UPI000007000F
EMBL: BC136652, AC016245, BC025180, BC073898, AB037724, AY090663, BC033258, GQ183898, CH471099, AC109327, BC064515, AC127496, BC136654, AC133012, AB082951
Ensembl: ENSG00000141564
KO: hsa:57521
Nucleutide sequences
EMBL-CDS: EAW89618.1, AAI36653.1, BAC06490.1, BAA92541.1, AAM09075.1, AAH64515.1, ACS44766.1, AAH25180.1, AAI36655.1, AAH33258.1, AAH73898.1
Ensembl_TRS: ENST00000570891, ENST00000544334, ENST00000306801
Protein sequencees
Ensembl_PRO: ENSP00000460136, ENSP00000442479, ENSP00000307272
RefSeq: NP_065812.1, NP_001156506.1
Others
UniRef100: UniRef100_Q8N122
UniRef90: UniRef90_Q8N122
UniRef50: UniRef50_Q8N122
UniGene: Hs.133044
CCDS: CCDS11773.1, CCDS54175.1

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