| Type | Description |
|---|---|
| Definition | G protein-coupled receptor 158 |
| Date | Results | Publications |
|---|---|---|
| 2020-09-12 11:56:00 | It findings implicate GPR158 as a homeostatic regulator of intraocular pressure and suggest GPR158 could be a pharmacological target for managing ocular hypertension. | 30855200 |
| 2020-02-15 10:46:00 | Elevated GPR158 expression patterns in mucinous ovarian carcinoma patients with unfavorable overall survival. | 31533654 |
| 2019-12-14 12:35:00 | Data observed that GPR158 interacted with and stabilized the amount of RGS7-beta5 through a 50-residue region downstream of its transmembrane domain and upstream of the VCPWE motifs. Also, two VCPWE motifs are involved in alphao binding. | 31189666 |
| 2019-08-10 11:57:00 | GPR158 is highly upregulated in the prefrontal cortex of human subjects with major depressive disorder. Exposure of mice to chronic stress also increased GPR158 protein levels in the prefrontal cortex in a glucocorticoid-dependent manner. | 29419376 |
| 2017-09-09 14:20:00 | Our results suggest that common ethnic-specific variation in GPR158 may influence energy expenditure (EE) in Pima Indians. rs11014566 nominally associated with measures of EE and adiposity, where the G allele associated with lower 24-h EE, lower higher BMI, and higher percent body fat. But, the association of rs11014566 with BMI did not directionally replicate when assessed in other ethnic groups. | 28476931 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
GP158_HUMAN
UniprotKB:
Q5T848
UniParc:
UPI0000199875
EMBL:
AL161654,
AL139821,
AB032962,
AY528411,
AL355587
Ensembl:
ENSG00000151025
KO:
hsa:57512
|
| Nucleutide sequences |
EMBL-CDS:
BAA86450.2,
AAS18315.1
Ensembl_TRS:
ENST00000376351
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000365529
RefSeq:
NP_065803.2,
XP_016871941.1
|
| Others |
UniRef100:
UniRef100_Q5T848
UniRef90:
UniRef90_Q5T848
UniRef50:
UniRef50_Q5T848
UniGene:
Hs.499108
CCDS:
CCDS31166.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员