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57496 MRTFB

57496

MRTFB

myocardin related transcription factor B

protein-coding

Homo sapiens

基因描述

Type Description
Definition myocardin related transcription factor B

研究结论

Date Results Publications
2021-02-20 13:30:00 The New Model of Snail Expression Regulation: The Role of MRTFs in Fast and Slow Endothelial-Mesenchymal Transition. 32824297
2020-04-25 12:43:00 Lower MRTFB expression levels are associated with shorter survival of patients with GI tract cancer. MRTFB targets SPDL1 and MCAM to inhibit CRC cell motility and tumor growth. Depletion of MRTFB in human CRC Cells increases cell motility and accelerates tumor growth in xenograft assays. 31690663
2019-09-07 11:03:00 Ectomesenchymal chondromyxoid tumors are characterized by an RREB1-MKL2 fusion gene. 29912715
2019-07-13 10:11:00 These studies implicate the actin cytoskeleton and ELK3, FLI1, and MKL2 in the transcriptional control of EDNRB and increase our understanding of the plasticity of this receptor 30332284
2019-06-15 11:11:00 Our new data identifies and important contribution of MKL1/2 to explaining the strikingly different response of VSMCs and ECs to cAMP elevation. Elucidation of these pathways promises to identify targets for specific inhibition of VSMC migration and proliferation. 28623279

名称对应

Type IDs
Synonymous MKL2, MRTF-B, NPD001
Gene
UniProtKB-ID: MRTFB_HUMAN
UniprotKB: Q9ULH7
UniParc: UPI000000DC52, UPI00001FEE5A, UPI00001B0649, UPI0000225CCB, UPI00001B07D4
EMBL: BC171750, AK294765, BC136260, AY374297, AC130650, CR749797, AK093577, BC047761, AC040173, CH471112, AB033069, AC012626
Ensembl: ENSG00000186260
KO: hsa:57496
Nucleutide sequences
EMBL-CDS: AAI71750.1, AAQ82435.1, AAH47761.1, AAI36261.1, CAH18657.1, BAC04200.1, BAA86557.2, BAG57899.1, EAW85112.1
Ensembl_TRS: ENST00000574045, ENST00000318282, ENST00000573051, ENST00000571589
Protein sequencees
Ensembl_PRO: ENSP00000459205, ENSP00000339086, ENSP00000459626, ENSP00000460589
RefSeq: NP_001352342.1, XP_006720977.1, NP_001352344.1, NP_001295071.1, XP_006720972.1, NP_001352341.1, XP_016878991.1, NP_001352340.1, XP_005255509.1, XP_011520870.1, NP_001352349.1, NP_001352348.1, XP_005255510.1, NP_001352343.1, XP_016878990.1, NP_001352345.1, XP_016878993.1, NP_054767.3, NP_001352347.1, NP_001352346.1, XP_016878992.1, XP_011520871.1, NP_001352350.1, XP_006720971.1
Others
UniRef100: UniRef100_Q9ULH7
UniRef90: UniRef90_Q9ULH7
UniRef50: UniRef50_P59759
UniGene: Hs.49143
CCDS: CCDS76823.1, CCDS32391.1

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研究热度

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