| Type | Description |
|---|---|
| Definition | extended synaptotagmin 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-06 13:28:00 | The short isoform of extended synaptotagmin-2 controls Ca(2+) dynamics in T cells via interaction with STIM1. | 32879390 |
| 2015-10-03 11:07:00 | ESyt2 and ESyt3, but not ESyt1, interact with activated FGFR1. | 25922075 |
| 2014-08-16 10:41:00 | 2.44 A resolution the crystal structure of a fragment of extended synaptotagmin 2, including an SMP domain and two adjacent C2 domains; evidence for a role of SMP-domain-containing proteins in the control of lipid transfer at membrane contact sites | 24847877 |
| 2013-08-31 12:04:00 | The extended synaptotagmins (E-Syt1, E-Syt2, and E-Syt3) are endoplasmic reticulum-anchored proteins. They form homo- and heteromeric complexes that mediate contacts with the plasma membrane. Such contacts are critically dependent on the presence of PI(4,5)P2 in this membrane and are additionally regulated by cytosolic Ca2+ via the Ca2+-sensing property of E-Syt1. | 23791178 |
| Type | IDs |
|---|---|
| Synonymous | CHR2SYT, E-Syt2, FAM62B |
| Gene |
UniProtKB-ID:
ESYT2_HUMAN
UniprotKB:
A0FGR8
UniParc:
UPI00002339BD,
UPI00001D7430,
UPI0001B9E74D,
UPI0000F0A539,
UPI0000F0A53A
EMBL:
AK126214,
AJ303365,
AL833233,
AB033054,
AK124091,
BC013957,
DQ993201,
AY368150,
AK001181,
CH236954
Ensembl:
ENSG00000117868
KO:
hsa:57488
|
| Nucleutide sequences |
EMBL-CDS:
EAL23931.1,
BAA86542.2,
CAC33887.1,
AAH13957.2,
CAH10642.1,
BAC86489.1,
AAR89381.1,
BAA91539.1,
ABJ97706.1,
BAC85769.1
Ensembl_TRS:
ENST00000652148
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000499020
RefSeq:
NP_065779.2,
XP_024302615.1,
XP_024302617.1,
XP_024302616.1,
XP_024302614.1,
NP_001354702.1
|
| Others |
UniRef100:
UniRef100_A0FGR8
UniRef90:
UniRef90_A0FGR8
UniRef50:
UniRef50_A0FGR8
UniGene:
Hs.490795
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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