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574503 MIR501

574503

MIR501

microRNA 501

ncRNA

Homo sapiens

基因描述

Type Description
Definition microRNA 501

研究结论

Date Results Publications
2020-10-31 13:15:00 MiR-501-3p functions as a tumor suppressor in non-small cell lung cancer by downregulating RAP1A. 31805277
2020-10-24 13:55:00 Inhibition of KHSRP sensitizes colorectal cancer to 5-fluoruracil through miR-501-5p-mediated ERRFI1 mRNA degradation. 31313286
2020-06-13 10:24:00 MiR-501 knockdown or BH3-like motif-containing protein, cell death inducer (BLID) overexpression could reverse the effects of ADR Exo on recipient cells. 31173853
2020-02-08 12:51:00 Results demonstrated that miR501 was overexpressed in colorectal cancer (CRC) tissues compared to the adjacent normal tissues. Its downregulation inhibited cell proliferation and sphere formation, while it induced cell cycle arrest at the G1 phase. Study identified miR501 as a novel regulator of Wnt/betacatenin signaling in CRC via targeting APC, suggesting that miR501 may act as a novel oncogenic miRNA in CRC. 31364752
2020-01-18 12:37:00 Highly expressed miR-501 was observed in pancreatic ductal adenocarcinoma (PDAC) tissues and tumor-associated macrophage (TAM)-derived exosomes. M2 macrophage-derived exosomal miR-501 inhibits tumor suppressor TGFBR3 gene and facilitates the development of PDAC by activating the TGF-beta signaling pathway 31307515

名称对应

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Type IDs
Synonymous MIRN501, hsa-mir-501, mir-501