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5745 PTH1R

5745

PTH1R

parathyroid hormone 1 receptor

protein-coding

Homo sapiens

基因描述

Type Description
Definition parathyroid hormone 1 receptor

研究结论

Date Results Publications
2020-11-21 13:17:00 Functional Analysis of PTH1R Variants Found in Primary Failure of Eruption. 31986066
2020-05-02 11:15:00 The oncogenic role of PTHLH appeared to be a consequence of its intracrine function, as downregulation of its receptor, PTH1R, increased anchorage-independent growth and induced a more undifferentiated, invasive phenotype. 31293052
2019-12-21 10:40:00 Type I collagen deposition was increased, whereas PTHR1 expression and type II collagen deposition were decreased by PTH supplementation. Expression of the (pre)hypertrophic markers MMP13, RUNX2, IHH and type X collagen were not affected by PTH 30947269
2019-12-07 12:00:00 PTHR1 may play important roles in progression of Osteosarcoma by activating miR-124-3p-AR-Tgfb1i1, miR-27a-3p-PPARG-Abca1, and miR-103/590-3p-AXIN2 axes. 31536386
2019-08-31 12:54:00 PTHR1 expression in U2OS cells was reduced by 0.18-, and 0.41-fold at 80, and 100 muM, respectively. 30978523

名称对应

Type IDs
Synonymous EKNS, PFE, PTHR, PTHR1
Gene
UniProtKB-ID: PTH1R_HUMAN, Q0VGD7_HUMAN, A1LPH3_HUMAN
UniprotKB: Q03431, Q0VGD7, A1LPH3
UniParc: UPI0000DBE1A2, UPI000005041F
EMBL: U22406, BC110388, U17418, U22401, CH471055, BC112247, U22408, L04308, U22404, U22403, X68596, BC112221, U22409, U22405, U22402, AY449732, U22407
Ensembl: ENSG00000160801
KO: hsa:5745
Nucleutide sequences
EMBL-CDS: CAA48589.1, AAA56774.1, AAI12248.1, AAB60657.1, AAR18076.1, AAI12222.1, AAA36525.1, AAI10389.1, EAW64793.1, EAW64794.1
Gene_ORFName: hCG_14653
Ensembl_TRS: ENST00000313049, ENST00000449590, ENST00000430002, ENST00000418619
Protein sequencees
Ensembl_PRO: ENSP00000413774, ENSP00000402723, ENSP00000321999, ENSP00000411424
RefSeq: NP_000307.1, XP_011532269.1, XP_016862423.1, XP_011532270.1, XP_005265401.1, XP_016862421.1, XP_016862422.1, NP_001171673.1
Others
UniRef100: UniRef100_Q03431, UniRef100_Q0VGD7
UniRef90: UniRef90_Q03431
UniRef50: UniRef50_Q03431
UniGene: Hs.1019
CCDS: CCDS2747.1

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