| Type | Description |
|---|---|
| Definition | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| Date | Results | Publications |
|---|---|---|
| 2019-10-19 10:46:00 | The homozygotes (knock-in mice with Xrcc2-c.T41C/p.Leu14Pro mutation) survived and exhibited meiotic arrest, azoospermia, premature ovarian failure and infertility. | 30042186 |
| 2017-09-09 10:43:00 | involvement of ZNF281 in the cellular response to genotoxic stress through the control exercised on the expression of genes that act in different repair mechanisms | 26300006 |
| 2011-06-04 10:52:00 | Data show that XRCC2 and other homologous recombination proteins, including the key recombinase RAD51, co-localize with the centrosome, potentially to coordinate the deployment of a DNA damage response at vulnerable phases of the cell cycle. | 21276791 |
| 2011-03-05 10:32:00 | These findings indicate that Xrcc2 haploinsufficiency reduces spontaneous tumor incidence on an Apc(min/+) background but increases the tumorigenic response to radiation. | 20671066 |
| 2010-08-02 12:08:00 | An important function of XRCC2 is to enhance the activity of RAD51, so that the loss of XRCC2 results in a severe delay in the early response of RAD51 to DNA damage. | 20189471 |
| Type | IDs |
|---|---|
| Synonymous | 4921524O04Rik, 8030409M04Rik, RAD51, RecA |
| Gene |
UniProtKB-ID:
XRCC2_MOUSE
UniprotKB:
Q9CX47
UniParc:
UPI0000001A9F
EMBL:
BC033417,
Y17040,
AK014963,
AK020192
Ensembl:
ENSMUSG00000028933
KO:
mmu:57434
|
| Nucleutide sequences |
EMBL-CDS:
BAB32023.1,
AAH33417.1,
CAA76599.1
Ensembl_TRS:
ENSMUST00000030773
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000030773
RefSeq:
NP_065595.2
|
| Others |
UniRef100:
UniRef100_Q9CX47
UniRef90:
UniRef90_Q9CX47
UniRef50:
UniRef50_O43543
UniGene:
Mm.143767
CCDS:
CCDS19135.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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