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5742 PTGS1

5742

PTGS1

prostaglandin-endoperoxide synthase 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition prostaglandin-endoperoxide synthase 1

研究结论

Date Results Publications
2021-03-20 13:34:00 A novel genetic variant in PTGS1 affects N-glycosylation of cyclooxygenase-1 causing a dominant-negative effect on platelet function and bleeding diathesis. 33326144
2021-02-06 13:53:00 Cyclooxygenase enzyme and PGE2 expression in patients with functional and non-functional pituitary adenomas. 32171274
2021-02-02 13:23:00 Serum agrin and talin are increased in major depression while agrin and creatine phosphokinase are associated with chronic fatigue and fibromyalgia symptoms in depression. 31734845
2021-01-16 15:56:00 Detection of novel mitochondrial mutations in cytochrome C oxidase subunit 1 (COX1) in patients with familial adenomatous polyposis (FAP). 31552592
2020-08-29 12:48:00 Valve Interstitial Cell-Specific Cyclooxygenase-1 Associated With Calcification of Aortic Valves. 31760051

名称对应

Type IDs
Synonymous COX1, COX3, PCOX1, PES-1, PGG/HS, PGHS-1, PGHS1, PHS1, PTGHS
Gene
UniProtKB-ID: PGH1_HUMAN, A0A087X296_HUMAN
UniprotKB: P23219, A0A087X296
UniParc: UPI00016EA8E5, UPI00027F7020, UPI00005913FD, UPI0001E7B046, UPI00005913FC, UPI0000161DAC, UPI0000160640
EMBL: M31815, AF440204, AY449688, M31822, AK290022, BC029840, DQ180741, AL359636, AK304403, DQ180742, CH471090, S78220, M31817, AK295221, M31813, S36271, M31814, M31821, M31816, M31812, M31819, M59979, AL162424, M31818, S36219, M31820
Ensembl: ENSG00000095303
KO: hsa:5742
Nucleutide sequences
EMBL-CDS: AAH29840.1, BAG65237.1, BAG58214.1, ABA60099.1, AAR08907.1, AAA36439.1, AAB21215.1, ABA60098.1, AAB22216.1, AAB22217.1, EAW87530.1, AAL33601.1, BAF82711.1, AAA03630.1
Ensembl_TRS: ENST00000223423, ENST00000362012, ENST00000540753, ENST00000373698, ENST00000619306
Protein sequencees
Ensembl_PRO: ENSP00000437709, ENSP00000362802, ENSP00000223423, ENSP00000354612, ENSP00000483540
RefSeq: NP_000953.2, NP_001258297.1, XP_024303383.1, NP_001258095.1, NP_542158.1, XP_024303382.1, XP_011517177.1, NP_001258094.1, XP_011517178.1, NP_001258296.1, NP_001258093.1, XP_005252162.1
Others
UniRef100: UniRef100_A0A087X296, UniRef100_P23219
UniRef90: UniRef90_P23219
UniRef50: UniRef50_O62698
UniGene: Hs.201978
CCDS: CCDS6842.1, CCDS59521.1, CCDS6843.1, CCDS59520.1

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