| Type | Description |
|---|---|
| Definition | NmrA like redox sensor 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-04-18 12:27:00 | Investigated the role of NmrA like redox sensor 1 (HSCARG), a cellular redox sensor. Demonstrated how HSCARG interacts with proliferating cell nuclear antigen (PCNA) in the translesion synthesis pathway, and showed that HSCARG, which is highly expressed in breast carcinoma, promotes accumulation of double stranded breaks and mutations. | 31796584 |
| 2016-10-01 10:57:00 | These findings suggest that the increased susceptibility of the G6PD-knockdown cells to viral infection was due to impaired NF-kappaB signaling and antiviral response mediated by HSCARG. | 26694452 |
| 2014-12-20 12:00:00 | After viral infection, HSCARG interacted with tumor necrosis receptor-associated factor 3 (TRAF3) and inhibited its ubiquitination by promoting the recruitment of OTUB1 to TRAF3. | 24763515 |
| 2014-10-25 10:05:00 | Data indicate that HSCARG and USP7 function in concert in inhibiting polyubiquination of NEMO, thus inhibiting NF-kappaB activity. | 24832601 |
| 2014-07-19 11:40:00 | HSCARG is involved in DNA damage response through affecting the level of H2A ubiquitination and localization of RAP80 at lesion points. | 24711370 |
| Type | IDs |
|---|---|
| Synonymous | HSCARG, SDR48A1 |
| Gene |
UniProtKB-ID:
NMRL1_HUMAN,
A0A384P622_HUMAN
UniprotKB:
Q9HBL8,
A0A384P622
UniParc:
UPI000007018F
EMBL:
GQ901038,
CH471112,
AF225419,
BC007364,
AC012676,
AC007606,
BC002927
Ensembl:
ENSG00000274684,
ENSG00000153406
KO:
hsa:57407
|
| Nucleutide sequences |
EMBL-CDS:
AAH07364.1,
AAG09721.1,
AAH02927.1,
ADO22555.1,
EAW85301.1
Gene_ORFName:
hCG_1984779
Ensembl_TRS:
ENST00000632013,
ENST00000633085,
ENST00000283429,
ENST00000616587,
ENST00000574733,
ENST00000621810,
ENST00000574425,
ENST00000404295
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000283429,
ENSP00000488644,
ENSP00000479569,
ENSP00000488692,
ENSP00000458762,
ENSP00000478990,
ENSP00000383962,
ENSP00000460263
RefSeq:
NP_001338923.1,
XP_016878976.1,
XP_011520869.1,
XP_006720968.1,
NP_001292071.1,
XP_016878975.1,
XP_016878977.1,
XP_016878978.1,
XP_016878974.1,
XP_006720969.1,
XP_024306128.1,
NP_001338924.1,
XP_016878980.1,
NP_065728.1,
NP_001292070.1,
NP_001338925.1
|
| Others |
UniRef100:
UniRef100_Q9HBL8
UniRef90:
UniRef90_Q9HBL8
UniRef50:
UniRef50_Q9HBL8
UniGene:
Hs.288969
CCDS:
CCDS10516.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员