| Type | Description |
|---|---|
| Definition | abhydrolase domain containing 6 |
| Date | Results | Publications |
|---|---|---|
| 2020-12-19 13:39:00 | Enhanced monoacylglycerol lipolysis by ABHD6 promotes NSCLC pathogenesis. | 32143183 |
| 2020-08-15 15:30:00 | It demonstrate that ABHD6 affect Bis(monoacylglycerol)phosphate (BMP) metabolism in mice and humans. | 30894461 |
| 2020-01-11 10:04:00 | We discovered a regulatory role of ABHD6 in human plasmacytoid dendritic cells (pDCs) through modulating the local abundance of its substrate, the endocannabinoid 2-arachidonyl glycerol (2-AG), and elucidated a hitherto unknown cannabinoid receptor 2-mediated regulatory role of 2-AG on IFN-alpha induction by pDCs. | 30728209 |
| 2018-05-19 12:02:00 | Data suggest that ABHD6 plays important role in regulation of signaling via monoacylglycerols (MAGs) in both central and peripheral tissues; alterations in MAG signaling are involved in type 2 diabetes, obesity, and metabolic syndrome. [REVIEW] | 28880480 |
| 2016-12-17 11:56:00 | The hydrolase activity of ABHD6 was not required for the effects of ABHD6 on AMPAR function in either neurons or transfected HEK293T cells. Thus, these findings reveal a novel and unexpected mechanism governing AMPAR trafficking at synapses through ABHD6. | 27114538 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
ABHD6_HUMAN,
A0A024R323_HUMAN
UniprotKB:
Q9BV23,
A0A024R323
UniParc:
UPI000003AF8F
EMBL:
BC001698,
AK172797,
CH471055,
AC137936,
AC098479,
AK122983,
AK313168
Ensembl:
ENSG00000163686
KO:
hsa:57406
|
| Nucleutide sequences |
EMBL-CDS:
AAH01698.1,
BAG53832.1,
BAD18771.1,
EAW65360.1,
BAG35986.1,
EAW65362.1,
EAW65365.1,
EAW65361.1
Gene_ORFName:
hCG_27734
Ensembl_TRS:
ENST00000295962,
ENST00000478253
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000295962,
ENSP00000420315
RefSeq:
NP_065727.4,
XP_005265392.1,
XP_005265391.1,
NP_001307055.1
|
| Others |
UniRef100:
UniRef100_Q9BV23
UniRef90:
UniRef90_Q8R2Y0
UniRef50:
UniRef50_Q8R2Y0
UniGene:
Hs.476454
CCDS:
CCDS2887.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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