| Type | Description |
|---|---|
| Definition | prostaglandin I2 receptor |
| Date | Results | Publications |
|---|---|---|
| 2017-12-09 10:26:00 | these studies are not only the first to identify alpha4 helix of Rab11a as a protein binding domain on the GTPase but also reveal novel mechanistic insights into the intracellular trafficking of the human prostacyclin receptor (hIP), and potentially of other members of the GPCR superfamily, involving Rab11-dependent mechanisms. | 28739266 |
| 2017-08-12 11:15:00 | role of IP-PPARdelta signal transduction pathway in the production of sAPPalpha in cerebral microvasculature. | 26661245 |
| 2017-06-10 10:12:00 | Data (including data from studies using transgenic mice, an murine experimental model of diabetes, and mouse/human cell lines) suggest prostaglandin I2 receptor (PTGIR) is involved in insulin secretion in pancreatic beta-cells and in permselectivity in glomerular podocytes; the mechanism appears to involve regulation of post-translational phosphorylation of nephrin. | 26868296 |
| 2017-06-03 12:16:00 | The human prostacyclin receptor gene is under the transcriptional regulation of dihydrotestosterone, where this regulation is further influenced by serum-cholesterol levels. | 27365208 |
| 2016-06-11 11:26:00 | cPGI2 generates via its cognate cell-surface receptor IP-R, converting white adipocytes to brite adipocytes. | 26775637 |
| Type | IDs |
|---|---|
| Synonymous | IP, PRIPR |
| Gene |
UniProtKB-ID:
PI2R_HUMAN
UniprotKB:
P43119
UniParc:
UPI000005042B
EMBL:
D25418,
AY242134,
D29634,
D38127,
L29016,
BC075814
Ensembl:
ENSG00000160013
KO:
hsa:5739
|
| Nucleutide sequences |
EMBL-CDS:
BAA05008.1,
BAA06110.1,
AAO92301.1,
AAA36448.1,
AAH75814.1,
BAA07325.1
Ensembl_TRS:
ENST00000291294
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000291294
RefSeq:
NP_000951.1,
XP_005259152.1,
XP_005259150.1
|
| Others |
UniRef100:
UniRef100_P43119
UniRef90:
UniRef90_P43119
UniRef50:
UniRef50_P43119
UniGene:
Hs.458324
CCDS:
CCDS12686.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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