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5737 PTGFR

5737

PTGFR

prostaglandin F receptor

protein-coding

Homo sapiens

基因描述

Type Description
Definition prostaglandin F receptor

研究结论

Date Results Publications
2018-09-08 11:51:00 Data, including data from studies using transgenic mice, suggest that signaling via prostaglandin-F2alpha/PTGFR and Camk2g/p38/Foxo1 MAP kinase/calcium pathways are involved in regulation of hepatic gluconeogenesis in both obesity and fasting. (PTGFR = prostaglandin F2alpha receptor; Camk2g = calcium-calmodulin-dependent protein kinase type 2 gamma; p38 = p38 MAP kinase; Foxo1 = forkhead box transcription factor O1) 29773555
2017-08-12 10:16:00 Data suggest that allosteric communication between heterodimeric AT1R and PTGFR is mediated through GNAQ and may also involve proximal phospholipase C but not distal protein kinase C signaling partners; PTGFR activation has negligible effects on AT1R-based conformational biosensors. (AT1R = angiotensin II receptor, type 1; PTGFR = prostaglandin F2alpha receptor; GNAQ = GTP-binding protein G[q] subunit alpha) 28584054
2017-05-20 11:44:00 The genotype frequencies of six SNPs in AFAP1, GMDS and PTGFR genes were conformed to Hardy-Weinberg equilibrium (HWE). 27862086
2016-04-09 10:10:00 these results indicated that the actions of AKR1C3 can produce FP receptor ligands whose activation results in carcinoma cell survival in breast cancer. 26170067
2015-10-24 10:49:00 The results indicated that the rs12731181 G allele of the Prostaglandin F2alpha Receptor Gene was associated with susceptibility to essential hypertension. 25977569

名称对应

Type IDs
Synonymous FP
Gene
UniProtKB-ID: PF2R_HUMAN
UniprotKB: P43088
UniParc: UPI00004CCF60, UPI00004CCF5D, UPI000022ABE6, UPI00004CCF5C, UPI0000001C40, UPI00004CCF5F, UPI00004CCF5E
EMBL: CH471059, L24470, AY485530, AB041713, AF004021, AL136324, AC096531, BC112965, AK292845, AY337000, AL158841
Ensembl: ENSG00000122420
KO: hsa:5737
Nucleutide sequences
EMBL-CDS: AAI12966.1, BAA94756.1, AAB63152.1, AAQ76788.1, BAF85534.1, AAA17684.1, AAR84381.1, EAX06351.1
Ensembl_TRS: ENST00000370757, ENST00000370756, ENST00000370758
Protein sequencees
Ensembl_PRO: ENSP00000359792, ENSP00000359793, ENSP00000359794
RefSeq: NP_000950.1, XP_016857362.1, NP_001034674.1
Others
UniRef100: UniRef100_P43088
UniRef90: UniRef90_P43088
UniRef50: UniRef50_P43088
UniGene: Hs.654365
CCDS: CCDS30759.1, CCDS686.1

全选

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